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Rabbit polyclonal CETN3 antibody (A8111)
Supplier: ABclonal Inc.
Recommended applications: WB,IHC
WB 1:500 – 1:2000 IHC 1:50 – 1:100
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit polyclonal CETN3 antibody.
Check alternative names for the antibodyExpand
CEN3 antibody, CDC31 antibody
CDC31 homolog antibody|CEN 3 antibody|CEN3 antibody|Centrin EF hand protein 3 antibody|Centrin-3 antibody|Centrin3 antibody|CETN 3 antibody|Cetn3 antibody|CETN3_HUMAN antibody|EF hand superfamily member antibody|MGC12502 antibody|MGC138245 antibody|Anti-Centrin 3 antibody (ab54531)
SCBT cat No: sc-365697|sc-100933|
Rabbit polyclonal CETN3 antibody
|Catalogue No.|| |
Human, Mouse, Rat
Recombinant protein of human CETN3
|Recommended dilution|| |
WB 1:500 – 1:2000
|Molecular weight|| |
Predicted: 20kDa/Observed: Refer to figures
CETN3 antibody was tube-contained.
CETN3 antibody was purified using affinity purification.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Alternative antibody names|| |
CEN3 antibody, CDC31 antibody
|Database links|| |
|Protein names|| |
|Protein function|| |
Plays a fundamental role in microtubule-organizing center structure and function.; Component of the TREX-2 complex (transcription and export complex 2), composed of at least ENY2, GANP, PCID2, DSS1, and either centrin CETN2 or CETN3 . The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery .
|Protein sequence and domain|| |
Belongs to the centrin family.; Contains 4 EF-hand domains.
|Protein cellular localization|| |
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Nucleus, nucleolus . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . Note: Centrosome of interphase and mitotic cells . Localizes to centriole distal lumen .
The protein encoded by this gene contains four EF-hand calcium binding domains, and is a member of the centrin protein family. Centrins are evolutionarily conserved proteins similar to the CDC31 protein of S. cerevisiae. Yeast CDC31 is located at the centrosome of interphase and mitotic cells, where it plays a fundamental role in centrosome duplication and separation. Multiple forms of the proteins similar to the yeast centrin have been identified in human and other mammalian cells, some of which have been shown to be associated with centrosome fractions. This protein appears to be one of the most abundant centrins associated with centrosome, which suggests a similar function to its yeast counterpart. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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|Product type|| |
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