Rabbit polyclonal CETN3 antibody (A8111)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal CETN3 antibody (A8111)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:100

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal CETN3 antibody.

Alternative names:

Check alternative names for the antibody

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CEN3 antibody, CDC31 antibody
CDC31 homolog antibody|CEN 3 antibody|CEN3 antibody|Centrin EF hand protein 3 antibody|Centrin-3 antibody|Centrin3 antibody|CETN 3 antibody|Cetn3 antibody|CETN3_HUMAN antibody|EF hand superfamily member antibody|MGC12502 antibody|MGC138245 antibody|Anti-Centrin 3 antibody (ab54531)

SCBT cat No: sc-365697|sc-100933|

Name

Rabbit polyclonal CETN3 antibody

Catalogue No.

A8111

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human CETN3

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:100

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 20kDa/Observed: Refer to figures

Formulation

CETN3 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

CETN3 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

CEN3 antibody, CDC31 antibody

Database links

Human UniProt/Swiss-Prot:O15182

Protein names

CEN3, CDC31

Protein function

Plays a fundamental role in microtubule-organizing center structure and function.; Component of the TREX-2 complex (transcription and export complex 2), composed of at least ENY2, GANP, PCID2, DSS1, and either centrin CETN2 or CETN3 . The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery .

Protein sequence and domain

Belongs to the centrin family.; Contains 4 EF-hand domains.

Protein cellular localization

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Nucleus, nucleolus . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . Note: Centrosome of interphase and mitotic cells . Localizes to centriole distal lumen .

Background

The protein encoded by this gene contains four EF-hand calcium binding domains, and is a member of the centrin protein family. Centrins are evolutionarily conserved proteins similar to the CDC31 protein of S. cerevisiae. Yeast CDC31 is located at the centrosome of interphase and mitotic cells, where it plays a fundamental role in centrosome duplication and separation. Multiple forms of the proteins similar to the yeast centrin have been identified in human and other mammalian cells, some of which have been shown to be associated with centrosome fractions. This protein appears to be one of the most abundant centrins associated with centrosome, which suggests a similar function to its yeast counterpart. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Note

AntibodyPlus can customize CETN3 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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