Rabbit polyclonal CHCHD3 antibody (A8584)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal CHCHD3 antibody (A8584)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:100

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal CHCHD3 antibody.

Alternative names:

Check alternative names for the antibody

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MINOS3 antibody, PPP1R22 antibody
CHCH3_HUMAN antibody|CHCHD 3 antibody|Chchd3 antibody|Coiled coil helix coiled coil helix domain containing 3 antibody|Coiled coil helix coiled coil helix domain containing protein 3 mitochondrial antibody|Coiled-coil-helix-coiled-coil-helix domain-containing protein 3 antibody|FLJ20420 antibody|MINOS3 antibody|mitochondrial antibody|Mitochondrial inner membrane organizing system 3 antibody|PPP1R22 antibody|Protein phosphatase 1 regulatory subunit 22 antibody|Anti-CHCHD3 antibody (ab69328)

SCBT cat No: sc-164059|

Name

Rabbit polyclonal CHCHD3 antibody

Catalogue No.

A8584

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human CHCHD3

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:100

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 26kDa/Observed: Refer to figures

Formulation

CHCHD3 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

CHCHD3 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

MINOS3 antibody, PPP1R22 antibody

Database links

Human UniProt/Swiss-Prot:Q9NX63

Protein names

MINOS3, PPP1R22

Protein function

Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Has also been shown to function as a transcription factor which binds to the BAG1 promoter and represses BAG1 transcription. Plays an important role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology .

Protein tissue specificity

Detected at low levels in brain, placenta, lung, liver, kidney and pancreas with increased levels in heart and skeletal muscle. Higher expression in primary lung cancers than in normal lung tissue.

Protein sequence and domain

Belongs to the MICOS complex subunit Mic19 family. Metazoan Mic19 subfamily.; Contains 1 CHCH domain.

Protein cellular localization

Mitochondrion inner membrane ; Lipid-anchor ; Intermembrane side . Cytoplasm . Nucleus . Mitochondrion .

Background

CHCHD3 (coiled-coil-helix-coiled-coil-helix domain containing 3) is a protein-coding gene. GO annotations related to this gene include phosphatase binding and RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription. An important paralog of this gene is CHCHD6.

Note

AntibodyPlus can customize CHCHD3 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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