Rabbit Polyclonal ChemR23 antibody (STJ92262)

$99.00$319.00

Reactivity: Human, Mouse, Rat
Applications: WB, IHC, IF, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal ChemR23 antibody (STJ92262)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, IHC, IF, ELISA

Recommended dilution: WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:20000;

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for ChemR23 Polyclonal Antibody.

Alternative names:

Check alternative names for the antibody

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CMKLR1 antibody, CHEMR23 antibody, DEZ antibody,|CHEMERINR antibody|Chemokine like receptor 1 antibody|Chemokine-like receptor 1 antibody|CHEMR23 antibody|CMKLR1 antibody|CML1_HUMAN antibody|DEZ antibody|G protein coupled receptor ChemR23 antibody|G protein coupled receptor DEZ antibody|G-protein coupled receptor ChemR23 antibody|G-protein coupled receptor DEZ antibody|Orphan G protein coupled receptor antibody|Orphan G protein coupled receptor Dez antibody|Resolvin E1 receptor antibody|RVER1 antibody|Anti-CMKLR1 antibody (ab64881)
SCBT cat No: sc-32652|

 

Name

ChemR23 Polyclonal Antibody

Catalogue No.

STJ92262

Reactivity

Human, Mouse, Rat

Specificity

ChemR23 Polyclonal Antibody detects endogenous levels of ChemR23 protein.

Immunogen

Synthesized peptide derived from ChemR23 at AA range 190-270

Host

Rabbit

Applications

WB, IHC, IF, ELISA

Recommended dilution

WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:20000;

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

42 kDa

Formulation

ChemR23 Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

ChemR23 Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Chemokine-like receptor 1 antibody, G-protein coupled receptor ChemR23 antibody, G-protein coupled receptor DEZ antibody

Database links

Human UniProt/Swiss-Prot:Q99788;Mouse UniPort/Swiss-Prot: P97468;Rat UniProt/Swiss-Port: G3V625;Human Entrez Gene: 1240;Mouse Entrez Gene: 14747;Rat Entrez Gene: Rn.44465

Protein names

Chemokine-like receptor 1 , G-protein coupled receptor ChemR23 , G-protein coupled receptor DEZ

Protein function

Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1. Interaction with RARRES2 induces activation of intracellular signaling molecules, such as SKY, MAPK1/3 (ERK1/2), MAPK14/P38MAPK and PI3K leading to multifunctional effects, like, reduction of immune responses, enhancing of adipogenesis and angionesis. Resolvin E1 down-regulates cytokine production in macrophages by reducing the activation of MAPK1/3 (ERK1/2) and NF-kappa-B. Positively regulates adipogenesis and adipocyte metabolism. Acts as a coreceptor for several SIV strains (SIVMAC316, SIVMAC239, SIVMACL7E-FR and SIVSM62A), as well as a primary HIV-1 strain (92UG024-2).

Protein tissue specificity

Prominently expressed in developing osseous and cartilaginous tissue. Also found in adult parathyroid glands. Expressed in cardiovascular system, brain, kidney, gastrointestinal tissues and myeloid tissues. Expressed in a broad array of tissues associated with hematopoietic and immune function including, spleen, thymus, appendix, lymph node, bone marrow and fetal liver. Among leukocyte populations abundant expression in monocyte-derived macrophage and immature dendritic cells (DCs). High expression in blood monocytes and low levels in polymorphonuclear cells and T-cells. Expressed on endothelial cells. Highly expressed in differentiating adipocytes.

Protein sequence and domain

Belongs to the G-protein coupled receptor 1 family.

Protein cellular localization

Cell membrane / Multi-pass membrane protein

Research area

All research areas>Membrane Receptors>ChemR23
(View all antibody categories related to Membrane Receptors)

Note

AntibodyPlus can customize ChemR23 Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

Reviews


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Antibody customer reviews & validation data - 62

Validation data ID: 62

Submission date: 2017-01-18

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Result figure:
Result figure

Figure description:

Western blot of whole cell lysates from 12 human vulvar fibroblast strains
8 ug of total protein per gel lane (far left and right lanes contained Mol. Wt. markers)

Product name

Rabbit Polyclonal GPR18 antibody (STJ93370); Rabbit Polyclonal ChemR23 antibody (STJ92262); Rabbit Polyclonal GPR32 antibody (STJ93378)

Product catalog No.

STJ93370,STJ92262,STJ93378

Product type

Primary antibody

Supplier

St John's Laboratory Ltd

Application type

Western Blot

Antibody specificity rating

Good

Antibody overall rating

Excellent

Your comments

GPR18 (#STJ93370) – Good; several bands of varying molecular weights appear, but the predicted 34 kDa band is evident
ChemR23 (#STJ92262) – Very good; predicted 42 kDa band is dominant signal with weak and minimal bands appearing at other molecular weights
GPR32 (#STJ93378) – Poor; very weak band appears at predicted molecular weight with considerable non-specific background signal throughout blot

Detailed protocol

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