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Rabbit Polyclonal ChemR23 antibody (STJ92262)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, IHC, IF, ELISA
Recommended dilution: WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:20000;
Recommended protocols: check protocols
Click or hover above images to see image description for ChemR23 Polyclonal Antibody.
Check alternative names for the antibodyExpand
CMKLR1 antibody, CHEMR23 antibody, DEZ antibody,|CHEMERINR antibody|Chemokine like receptor 1 antibody|Chemokine-like receptor 1 antibody|CHEMR23 antibody|CMKLR1 antibody|CML1_HUMAN antibody|DEZ antibody|G protein coupled receptor ChemR23 antibody|G protein coupled receptor DEZ antibody|G-protein coupled receptor ChemR23 antibody|G-protein coupled receptor DEZ antibody|Orphan G protein coupled receptor antibody|Orphan G protein coupled receptor Dez antibody|Resolvin E1 receptor antibody|RVER1 antibody|Anti-CMKLR1 antibody (ab64881)
SCBT cat No: sc-32652|
ChemR23 Polyclonal Antibody
|Catalogue No.|| |
Human, Mouse, Rat
ChemR23 Polyclonal Antibody detects endogenous levels of ChemR23 protein.
Synthesized peptide derived from ChemR23 at AA range 190-270
WB, IHC, IF, ELISA
|Recommended dilution|| |
WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:20000;
|Molecular weight|| |
ChemR23 Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
ChemR23 Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Chemokine-like receptor 1 antibody, G-protein coupled receptor ChemR23 antibody, G-protein coupled receptor DEZ antibody
|Protein names|| |
Chemokine-like receptor 1 , G-protein coupled receptor ChemR23 , G-protein coupled receptor DEZ
|Protein function|| |
Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1. Interaction with RARRES2 induces activation of intracellular signaling molecules, such as SKY, MAPK1/3 (ERK1/2), MAPK14/P38MAPK and PI3K leading to multifunctional effects, like, reduction of immune responses, enhancing of adipogenesis and angionesis. Resolvin E1 down-regulates cytokine production in macrophages by reducing the activation of MAPK1/3 (ERK1/2) and NF-kappa-B. Positively regulates adipogenesis and adipocyte metabolism. Acts as a coreceptor for several SIV strains (SIVMAC316, SIVMAC239, SIVMACL7E-FR and SIVSM62A), as well as a primary HIV-1 strain (92UG024-2).
|Protein tissue specificity|| |
Prominently expressed in developing osseous and cartilaginous tissue. Also found in adult parathyroid glands. Expressed in cardiovascular system, brain, kidney, gastrointestinal tissues and myeloid tissues. Expressed in a broad array of tissues associated with hematopoietic and immune function including, spleen, thymus, appendix, lymph node, bone marrow and fetal liver. Among leukocyte populations abundant expression in monocyte-derived macrophage and immature dendritic cells (DCs). High expression in blood monocytes and low levels in polymorphonuclear cells and T-cells. Expressed on endothelial cells. Highly expressed in differentiating adipocytes.
|Protein sequence and domain|| |
Belongs to the G-protein coupled receptor 1 family.
|Protein cellular localization|| |
Cell membrane / Multi-pass membrane protein
AntibodyPlus can customize ChemR23 Antibody according to your requirement, including bulk product size,etc. Please contact email@example.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.
St John’s Laboratory Ltd.
|Product type|| |
Displaying 1 - 1 of 1
Antibody customer reviews & validation data - 62
Validation data ID: 62
Submission date: 2017-01-18
Western blot of whole cell lysates from 12 human vulvar fibroblast strains
8 ug of total protein per gel lane (far left and right lanes contained Mol. Wt. markers)
Rabbit Polyclonal GPR18 antibody (STJ93370); Rabbit Polyclonal ChemR23 antibody (STJ92262); Rabbit Polyclonal GPR32 antibody (STJ93378)
Product catalog No.
St John's Laboratory Ltd
Antibody specificity rating
Antibody overall rating
GPR18 (#STJ93370) – Good; several bands of varying molecular weights appear, but the predicted 34 kDa band is evident
ChemR23 (#STJ92262) – Very good; predicted 42 kDa band is dominant signal with weak and minimal bands appearing at other molecular weights
GPR32 (#STJ93378) – Poor; very weak band appears at predicted molecular weight with considerable non-specific background signal throughout blot
There is no extra validation for this product yet.
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