Rabbit polyclonal CHIT1 antibody (A2015)

$69.00$259.00

Reactivity: Human
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal CHIT1 antibody (A2015)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal CHIT1 antibody.

Alternative names:

Check alternative names for the antibody

Expand

CHI3 antibody, CHIT antibody, CHITD antibody
CHI3 antibody|CHIT antibody|CHIT1 antibody|CHIT1_HUMAN antibody|CHITD antibody|Chitinase 1 antibody|Chitinase 1 (chitotriosidase) antibody|Chitinase-1 antibody|Chitotriosidase antibody|Chitotriosidase-1 antibody|EC 3.2.1.14 antibody|FLJ00314 antibody|MGC125322 antibody|Plasma methylumbelliferyl tetra N acetylchitotetraoside hydrolase antibody|Anti-CHIT1 antibody (ab96045)

SCBT cat No: sc-271460|sc-271282|sc-46853|sc-46854|sc-99033|

Name

Rabbit polyclonal CHIT1 antibody

Catalogue No.

A2015

Reactivity

Human

Immunogen

Recombinant protein of human CHIT1

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 52kDa/Observed: Refer to figures

Formulation

CHIT1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

CHIT1 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

CHI3 antibody, CHIT antibody, CHITD antibody

Database links

Human UniProt/Swiss-Prot:Q13231

Protein names

CHI3, CHIT, CHITD

Protein function

Degrades chitin, chitotriose and chitobiose. May participate in the defense against nematodes and other pathogens. Isoform 3 has no enzymatic activity.

Protein tissue specificity

Detected in spleen. Secreted by cultured macrophages.

Protein sequence and domain

Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.; Contains 1 chitin-binding type-2 domain.

Protein cellular localization

Secreted. Lysosome. Note: A small proportion is lysosomal.

Background

Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. Several alternatively spliced transcript variants have been described for this gene.

Research area

All research areas>Lymphocyte Signaling>Chitotriosidase
(View all antibody categories related to Lymphocyte Signaling)

Note

AntibodyPlus can customize CHIT1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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