Rabbit polyclonal CHRFAM7A antibody (A7844)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal CHRFAM7A antibody (A7844)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal CHRFAM7A antibody.

Alternative names:

Check alternative names for the antibody

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D-10 antibody, CHRNA7 antibody, CHRNA7-DR1 antibody
Alpha 7 neuronal nicotinic acetylcholine receptor FAM7A hybrid antibody|CHRNA7 (cholinergic receptor nicotinic alpha 7 exons 5 10) and FAM7A (family with sequence similarity 7A exons A E) fusion antibody|CHRNA7 antibody|CHRNA7 DR1 antibody|CHRNA7 FAM7A fusion antibody|CHRNA7 FAM7A fusion protein antibody|D 10 antibody|D10 antibody|MGC120482 antibody|MGC120483 antibody|Anti-CHRFAM7A antibody (ab198719)

SCBT cat No:

Name

Rabbit polyclonal CHRFAM7A antibody

Catalogue No.

A7844

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human CHRFAM7A

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 46kDa/Observed: Refer to figures

Formulation

CHRFAM7A antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

CHRFAM7A antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

D-10 antibody, CHRNA7 antibody, CHRNA7-DR1 antibody

Database links

Human UniProt/Swiss-Prot:Q494W8

Protein names

D-10, CHRNA7, CHRNA7-DR1

Protein tissue specificity

Expressed in hippocampus.

Protein sequence and domain

Belongs to the ligand-gated ion channel (TC 1.A.9) family.

Protein cellular localization

Membrane ; Multi-pass membrane protein .

Background

The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The family member CHRNA7, which is located on chromosome 15 in a region associated with several neuropsychiatric disorders, is partially duplicated and forms a hybrid with a novel gene from the family with sequence similarity 7 (FAM7A). Alternative splicing has been observed, and two variants exist, for this hybrid gene. The N-terminally truncated products predicted by the largest open reading frames for each variant would lack the majority of the neurotransmitter-gated ion-channel ligand binding domain but retain the transmembrane region that forms the ion channel. Although current evidence supports transcription of this hybrid gene, translation of the nicotinic acetylcholine receptor-like protein-encoding open reading frames has not been confirmed.

Note

AntibodyPlus can customize CHRFAM7A antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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