Rabbit polyclonal CHRM2 antibody (A1567)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal CHRM2 antibody (A1567)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal CHRM2 antibody.

Alternative names:

Check alternative names for the antibody

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CHRM2 antibody,FLJ43243 antibody,HM2 antibody,MGC120006 antibody,MGC120007 antibody
7TM receptor antibody|Acetylcholine receptor, muscarinic, 2 antibody|AChR antibody|Acm2 antibody|ACM2_HUMAN antibody|Cholinergic receptor muscarinic 2 antibody|Cholinergic receptor, muscarinic 2, cardiac antibody|Cholinergic receptor, muscarinic 2, isoform a antibody|Cholinergic receptor, muscarinic 2a antibody|CHRM 2 antibody|CHRM2 antibody|chrm2a antibody|CM2 antibody|FLJ43243 antibody|HM 2 antibody|HM2 antibody|M2 antibody|M2 muscarinic receptor antibody|M2-mAChR antibody|MGC120006 antibody|MGC120007 antibody|Muscarinic acetylcholine receptor M2 antibody|Muscarinic M2 receptor antibody|Anti-Muscarinic Acetylcholine Receptor 2 antibody [31-1D1] (ab2805)

SCBT cat No: sc-71531|sc-80971|sc-7472|sc-9107|sc-31483|sc-33712|

Name

Rabbit polyclonal CHRM2 antibody

Catalogue No.

A1567

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human CHRM2

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 52kDa/Observed: Refer to Figures

Formulation

CHRM2 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

CHRM2 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

CHRM2 antibody,FLJ43243 antibody,HM2 antibody,MGC120006 antibody,MGC120007 antibody

Database links

Human UniProt/Swiss-Prot:P08172

Protein names

CHRM2,FLJ43243,HM2,MGC120006,MGC120007

Protein function

The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is adenylate cyclase inhibition. Signaling promotes phospholipase C activity, leading to the release of inositol trisphosphate (IP3); this then triggers calcium ion release into the cytosol.

Protein sequence and domain

Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHRM2 sub-subfamily.

Protein post-translational modifications

Phosphorylated in response to agonist treatment.

Protein cellular localization

Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Note: Phosphorylation in response to agonist binding promotes receptor internalization.

Background

The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 2 is involved in mediation of bradycardia and a decrease in cardiac contractility. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2008]

Research area

All research areas>Neurobiology>mAChR M
(View all antibody categories related to Neurobiology)

Note

AntibodyPlus can customize CHRM2 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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