Rabbit polyclonal CHRNA1 antibody (A5306)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal CHRNA1 antibody (A5306)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal CHRNA1 antibody.

Alternative names:

Check alternative names for the antibody

Expand

ACHRA antibody, ACHRD antibody, CHRNA antibody, CMS2A antibody, FCCMS antibody, SCCMS antibody
Acetylcholine receptor subunit alpha antibody|ACHA_HUMAN antibody|AChR antibody|ACHRA antibody|CHNRA antibody|Cholinergic receptor nicotinic alpha polypeptide 1 antibody|Cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle) antibody|Chrna1 antibody|Nicotinic cholinergic receptor alpha 1 antibody|Schizophrenia neurophysiologic defect candidate antibody|Anti-Nicotinic Acetylcholine Receptor alpha 1 antibody (ab28489)

SCBT cat No: sc-32253|sc-32252|sc-1442|sc-292790|

Name

Rabbit polyclonal CHRNA1 antibody

Catalogue No.

A5306

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human CHRNA1

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 31kDa/Observed: Refer to Figures

Formulation

CHRNA1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

CHRNA1 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

ACHRA antibody, ACHRD antibody, CHRNA antibody, CMS2A antibody, FCCMS antibody, SCCMS antibody

Database links

Human UniProt/Swiss-Prot:P02708

Protein names

ACHRA, ACHRD, CHRNA, CMS2A, FCCMS, SCCMS

Protein function

After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.

Protein tissue specificity

Isoform 1 is only expressed in skeletal muscle. Isoform 2 is constitutively expressed in skeletal muscle, brain, heart, kidney, liver, lung and thymus.

Protein sequence and domain

Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Alpha-1/CHRNA1 sub-subfamily.

Protein cellular localization

Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.

Background

The muscle acetylcholine receptor consiststs of 5 subunits of 4 different types: 2 alpha subunits and 1 each of the beta, gamma, and delta subunits. This gene encodes an alpha subunit that plays a role in acetlycholine binding/channel gating. Alternatively spliced transcript variants encoding different isoforms have been identified.

Research area

All research areas>Channel Proteins>AChR
(View all antibody categories related to Channel Proteins)

Note

AntibodyPlus can customize CHRNA1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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