Rabbit polyclonal CHRNA4 antibody (A1648)

$69.00$259.00

Reactivity: Mouse
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal CHRNA4 antibody (A1648)

Supplier: ABclonal Inc.

Recommended applications: WB

Recommended dilution:

WB 1:500 – 1:2000

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal CHRNA4 antibody.

Alternative names:

Check alternative names for the antibody

Expand

EBN antibody, BFNC antibody, EBN1 antibody, NACHR antibody, NACRA4 antibody, NACHRA4 antibody
A4 nicotinic receptor antibody|Acetylcholine receptor alpha 4 neural antibody|Acetylcholine receptor neuronal nicotinic alpha 4 subunit antibody|ACH 4 antibody|ACH4 antibody|ACHA4_HUMAN antibody|AChR antibody|Acra 4 antibody|Acra4 antibody|Alpha4 nAChR antibody|BFNC antibody|Cholinergic receptor nicotinic alpha 4 antibody|Cholinergic receptor nicotinic alpha polypeptide 4 antibody|CHRNA 4 antibody|CHRNA4 antibody|EBN 1 antibody|EBN antibody|EBN1 antibody|NACHR antibody|NACRA 4 antibody|NACRA4 antibody|Neuronal acetylcholine receptor subunit alpha-4 antibody|Neuronal nicotinic acetylcholine receptor alpha 4 subunit antibody|Anti-Nicotinic Acetylcholine Receptor alpha 4 antibody (ab41172)

SCBT cat No: sc-65862|sc-1772|sc-74519|sc-5591|

Name

Rabbit polyclonal CHRNA4 antibody

Catalogue No.

A1648

Reactivity

Mouse

Immunogen

Recombinant protein of human CHRNA4

Host

Rabbit

Applications

WB

Recommended dilution

WB 1:500 – 1:2000

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 70kDa/Observed: Refer to figures

Formulation

CHRNA4 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

CHRNA4 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

EBN antibody, BFNC antibody, EBN1 antibody, NACHR antibody, NACRA4 antibody, NACHRA4 antibody

Database links

Human UniProt/Swiss-Prot:P43681

Protein names

EBN, BFNC, EBN1, NACHR, NACRA4, NACHRA4

Protein function

After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane permeable to sodium ions.

Protein sequence and domain

Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Alpha-4/CHRNA4 sub-subfamily.

Protein cellular localization

Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cell membrane ; Lipid-anchor .

Background

This gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have been described. Alternative splicing results in multiple transcript variants.

Research area

All research areas>Channel Proteins>AChR
(View all antibody categories related to Channel Proteins)

Note

AntibodyPlus can customize CHRNA4 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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