Rabbit polyclonal CHRNG antibody (A7884)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal CHRNG antibody (A7884)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal CHRNG antibody.

Alternative names:

Check alternative names for the antibody

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ACHRG antibody
Acetylcholine receptor muscle gamma subunit antibody|Acetylcholine receptor protein gamma chain precursor antibody|Acetylcholine receptor subunit gamma antibody|ACHG antibody|ACHG_HUMAN antibody|Achr 3 antibody|AChR antibody|Achr3 antibody|ACHRG antibody|ACRG antibody|Cholinergic receptor nicotinic gamma antibody|Cholinergic receptor nicotinic gamma polypeptide antibody|CHRNG antibody|MGC133376 antibody|Anti-Nicotinic Acetylcholine Receptor gamma antibody [66] (ab24667)

SCBT cat No: sc-58597|sc-1453|sc-13998|

Name

Rabbit polyclonal CHRNG antibody

Catalogue No.

A7884

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human CHRNG

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 58kDa/Observed: Refer to figures

Formulation

CHRNG antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

CHRNG antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

ACHRG antibody

Database links

Human UniProt/Swiss-Prot:P07510

Protein names

ACHRG

Protein function

After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.

Protein sequence and domain

Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Gamma/CHRNG sub-subfamily.

Protein cellular localization

Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.

Background

The mammalian muscle-type acetylcholine receptor is a transmembrane pentameric glycoprotein with two alpha subunits, one beta, one delta, and one epsilon (in adult skeletal muscle) or gamma (in fetal and denervated muscle) subunit. This gene, which encodes the gamma subunit, is expressed prior to the thirty-third week of gestation in humans. The gamma subunit of the acetylcholine receptor plays a role in neuromuscular organogenesis and ligand binding and disruption of gamma subunit expression prevents the correct localization of the receptor in cell membranes. Mutations in this gene cause Escobar syndrome and a lethal form of multiple pterygium syndrome. Muscle-type acetylcholine receptor is the major antigen in the autoimmune disease myasthenia gravis.

Research area

All research areas>Channel Proteins>AChR
(View all antibody categories related to Channel Proteins)

Note

AntibodyPlus can customize CHRNG antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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