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Rabbit polyclonal CHRNG antibody (A7884)
Supplier: ABclonal Inc.
Recommended applications: WB,IHC
WB 1:500 – 1:2000 IHC 1:50 – 1:200
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit polyclonal CHRNG antibody.
Check alternative names for the antibodyExpand
Acetylcholine receptor muscle gamma subunit antibody|Acetylcholine receptor protein gamma chain precursor antibody|Acetylcholine receptor subunit gamma antibody|ACHG antibody|ACHG_HUMAN antibody|Achr 3 antibody|AChR antibody|Achr3 antibody|ACHRG antibody|ACRG antibody|Cholinergic receptor nicotinic gamma antibody|Cholinergic receptor nicotinic gamma polypeptide antibody|CHRNG antibody|MGC133376 antibody|Anti-Nicotinic Acetylcholine Receptor gamma antibody  (ab24667)
SCBT cat No: sc-58597|sc-1453|sc-13998|
Rabbit polyclonal CHRNG antibody
|Catalogue No.|| |
Human, Mouse, Rat
Recombinant protein of human CHRNG
|Recommended dilution|| |
WB 1:500 – 1:2000
|Molecular weight|| |
Predicted: 58kDa/Observed: Refer to figures
CHRNG antibody was tube-contained.
CHRNG antibody was purified using affinity purification.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Alternative antibody names|| |
|Database links|| |
|Protein names|| |
|Protein function|| |
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
|Protein sequence and domain|| |
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Gamma/CHRNG sub-subfamily.
|Protein cellular localization|| |
Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
The mammalian muscle-type acetylcholine receptor is a transmembrane pentameric glycoprotein with two alpha subunits, one beta, one delta, and one epsilon (in adult skeletal muscle) or gamma (in fetal and denervated muscle) subunit. This gene, which encodes the gamma subunit, is expressed prior to the thirty-third week of gestation in humans. The gamma subunit of the acetylcholine receptor plays a role in neuromuscular organogenesis and ligand binding and disruption of gamma subunit expression prevents the correct localization of the receptor in cell membranes. Mutations in this gene cause Escobar syndrome and a lethal form of multiple pterygium syndrome. Muscle-type acetylcholine receptor is the major antigen in the autoimmune disease myasthenia gravis.
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|Product type|| |
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