Rabbit polyclonal CIAPIN1 antibody (A6336)

$69.00$259.00

Reactivity: Human,Mouse
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal CIAPIN1 antibody (A6336)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

Expand

DRE2 antibody, PRO0915 antibody, Anamorsin antibody, 2810413N20Rik antibody
2810413N20Rik antibody|Anamorsin antibody|CIAPIN 1 antibody|CIAPIN1 antibody|CPIN1_HUMAN antibody|Cytokine induced apoptosis inhibitor 1 antibody|Cytokine-induced apoptosis inhibitor 1 antibody|DRE2 antibody|Fe-S cluster assembly protein DRE2 homolog antibody|Predicted protein of HQ0915 antibody|PRO0915 antibody|Anti-CIAPIN1 antibody (ab154904)

SCBT cat No: sc-271298|sc-134449|

Name

Rabbit polyclonal CIAPIN1 antibody

Catalogue No.

A6336

Reactivity

Human, Mouse

Immunogen

Recombinant protein of human CIAPIN1

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 33kDa/Observed: Refer to Figures

Formulation

CIAPIN1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

CIAPIN1 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

DRE2 antibody, PRO0915 antibody, Anamorsin antibody, 2810413N20Rik antibody

Database links

Human UniProt/Swiss-Prot:Q6FI81

Protein names

DRE2, PRO0915, Anamorsin, 2810413N20Rik

Protein function

Has anti-apoptotic effects in the cell. Involved in negative control of cell death upon cytokine withdrawal. Promotes development of hematopoietic cells (By similarity). Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Electrons are transferred to the Fe-S cluster from NADPH via the FAD- and FMN-containing protein NDOR1.

Protein tissue specificity

Ubiquitously expressed. Highly expressed in heart, liver and pancreas.

Protein sequence and domain

The N-terminal domain has structural similarity with S-adenosyl-L-methionine-dependent methyltransferases, but does not bind S-adenosyl-L-methionine.; The C-terminal domain binds one 2Fe-2S iron-sulfur cluster but is otherwise mostly in an intrinsically disordered conformation.; The twin Cx2C motifs are involved in the recognition by the mitochondrial CHCHD4/MIA40-GFER/ERV1 disulfide relay system. The formation of 2 disulfide bonds in the Cx2C motifs through dithiol/disulfide exchange reactions effectively traps the protein in the mitochondrial intermembrane space.Belongs to the anamorsin family.

Protein cellular localization

Cytoplasm. Nucleus. Mitochondrion. Mitochondrion intermembrane space . Note: Imported into mitochondria (in vitro).

Background

CIAPIN1 is a cytokine-induced inhibitor of apoptosis with no relation to apoptosis regulatory molecules of the BCL2 (MIM 151430) or CASP (see MIM 147678) families. Expression of CIAPIN1 is dependent on growth factor stimulation (Shibayama et al., 2004

Note

AntibodyPlus can customize CIAPIN1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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