Rabbit polyclonal CIRH1A antibody (A8593)

A8593

Recombinant protein of human CIRH1A

WB

Polyclonal

IgG

CIRH1A antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Human UniProt/Swiss-Prot:Q969X6

May be a transcriptional regulator. Acts as a positive regulator of HIVEP1 which specifically binds to the DNA sequence 5′-GGGACTTTCC-3′ found in enhancer elements of numerous viral promoters such as those of HIV-1, SV40, or CMV. Ribosome biogenesis factor involved in small subunit (SSU) pre-rRNA processing at sites A’, A0, 1 and 2b.

May be phosphorylated during mitosis; may control the association of this protein with WRD43 and UTP15.

This gene encodes a WD40-repeat-containing protein that is localized to the nucleolus. Mutation of this gene causes North American Indian childhood cirrhosis, a severe intrahepatic cholestasis that results in transient neonatal jaundice, and progresses to periportal fibrosis and cirrhosis in childhood and adolescence.

Primary antibody