Rabbit polyclonal CKAP5 antibody (A8532)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal CKAP5 antibody (A8532)

Supplier: ABclonal Inc.

Recommended applications: WB

Recommended dilution:

WB 1:500 – 1:2000

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal CKAP5 antibody.

Alternative names:

Check alternative names for the antibody

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TOG antibody, MSPS antibody, TOGp antibody, CHTOG antibody, ch-TOG antibody
Ch TOG protein antibody|chTOG antibody|CHTOG protein antibody|CKAP 5 antibody|CKAP5 antibody|CKAP5 protein antibody|Colonic and hepatic tumor over expressed antibody|Colonic and hepatic tumor over expressed protein antibody|Colonic and hepatic tumor overexpressed protein antibody|Cytoskeleton associated protein 5 antibody|FLJ35359 antibody|KIAA0097 antibody|TOG antibody|TOGp antibody|Anti-ch TOG antibody (ab86073)

SCBT cat No: sc-240235|sc-374394|

Name

Rabbit polyclonal CKAP5 antibody

Catalogue No.

A8532

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human CKAP5

Host

Rabbit

Applications

WB

Recommended dilution

WB 1:500 – 1:2000

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 225kDa/Observed: Refer to Figures

Formulation

CKAP5 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

CKAP5 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

TOG antibody, MSPS antibody, TOGp antibody, CHTOG antibody, ch-TOG antibody

Database links

Human UniProt/Swiss-Prot:Q14008

Protein names

TOG, MSPS, TOGp, CHTOG, ch-TOG

Protein function

Binds to the plus end of microtubules and regulates microtubule dynamics and microtubule organization. Promotes cytoplasmic microtubule nucleation and elongation. Plays a major role in organizing spindle poles.

Protein tissue specificity

Overexpressed in hepatomas and colonic tumors. Also expressed in skeletal muscle, brain, heart, placenta, lung, liver, kidney and pancreas.

Protein sequence and domain

Belongs to the TOG/XMAP215 family.; Contains 10 HEAT repeats.

Protein cellular localization

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, spindle pole . Note: Detected on centrosomes during interphase. Detected on spindle poles and microtubules during mitosis.

Background

This gene encodes a cytoskeleton-associated protein which belongs to the TOG/XMAP215 family. The N-terminal half of this protein contains a microtubule-binding domain and the C-terminal half contains a KXGS motif for binding tubulin dimers. This protein has two distinct roles in spindle formation; it protects kinetochore microtubules from depolymerization and plays an essential role in centrosomal microtubule assembly. This protein may be necessary for the proper interaction of microtubules with the cell cortex for directional cell movement. It also plays a role in translation of the myelin basic protein (MBP) mRNA by interacting with heterogeneous nuclear ribonucleoprotein (hnRNP) A2, which associates with MBP. Alternatively spliced transcript variants encoding different isoforms have been identified.

Note

AntibodyPlus can customize CKAP5 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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