Rabbit polyclonal CLCN1 antibody (A5739)

$69.00$259.00

Reactivity: Human,Mouse
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal CLCN1 antibody (A5739)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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CLC1 antibody
Chloride channel protein 1 antibody|Chloride channel protein antibody|Chloride channel protein skeletal muscle antibody|CIC 1 antibody|CIC1 antibody|ClC-1 antibody|CLC1 antibody|Clcn1 antibody|CLCN1_HUMAN antibody|MGC138361 antibody|MGC142055 antibody|skeletal muscle antibody|Anti-CLCN1 antibody – C-terminal (ab189857)

SCBT cat No: sc-16426|sc-25699|

Name

Rabbit polyclonal CLCN1 antibody

Catalogue No.

A5739

Reactivity

Human, Mouse

Immunogen

Recombinant protein of human CLCN1

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 108kDa/Observed: Refer to Figures

Formulation

CLCN1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

CLCN1 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

CLC1 antibody

Database links

Human UniProt/Swiss-Prot:P35523

Protein names

CLC1

Protein function

Voltage-gated chloride channel. Chloride channels have several functions including the regulation of cell volume; membrane potential stabilization, signal transduction and transepithelial transport.

Protein tissue specificity

Predominantly expressed in skeletal muscles.

Protein sequence and domain

Belongs to the chloride channel (TC 2.A.49) family. ClC-1/CLCN1 subfamily.; Contains 2 CBS domains.

Protein cellular localization

Cell membrane ; Multi-pass membrane protein .

Background

The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7, Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology. The protein encoded by this gene regulates the electric excitability of the skeletal muscle membrane. Mutations in this gene cause two forms of inherited human muscle disorders: recessive generalized myotonia congenita (Becker) and dominant myotonia (Thomsen). Alternative splicing results in multiple transcript variants.

Research area

All research areas>Channel Proteins>CLC
(View all antibody categories related to Channel Proteins)

Note

AntibodyPlus can customize CLCN1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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