Rabbit polyclonal CLCN5 antibody (A5707)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal CLCN5 antibody (A5707)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:20 – 1:100

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal CLCN5 antibody.

Alternative names:

Check alternative names for the antibody

Expand

XRN antibody, CLC5 antibody, XLRH antibody, CLCK2 antibody, ClC-5 antibody, DENTS antibody, NPHL1 antibody, NPHL2 antibody, hCIC-K2 antibody
Chloride channel protein 5 antibody|Chloride channel voltage sensitive 5 antibody|Chloride transporter ClC-5 antibody|ClC-5 antibody|CLC5 antibody|CLCK2 antibody|CLCN5 antibody|CLCN5_HUMAN antibody|DENTS antibody|H(+)/Cl(-) exchange transporter 5 antibody|hCIC-K2 antibody|NPHL1 antibody|NPHL2 antibody|Voltage gated chloride ion channel CLCN5 antibody|XLRH antibody|XRN antibody|Anti-Chloride Channel 5 antibody – C-terminal (ab188503)

SCBT cat No: sc-390010|sc-17572|

Name

Rabbit polyclonal CLCN5 antibody

Catalogue No.

A5707

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human CLCN5

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:20 – 1:100

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 83kDa/Observed: Refer to Figures

Formulation

CLCN5 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

CLCN5 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

XRN antibody, CLC5 antibody, XLRH antibody, CLCK2 antibody, ClC-5 antibody, DENTS antibody, NPHL1 antibody, NPHL2 antibody, hCIC-K2 antibody

Database links

Human UniProt/Swiss-Prot:P51795

Protein names

XRN, CLC5, XLRH, CLCK2, ClC-5, DENTS, NPHL1, NPHL2, hCIC-K2

Protein function

Proton-coupled chloride transporter. Functions as antiport system and exchanges chloride ions against protons. Important for normal acidification of the endosome lumen. May play an important role in renal tubular function.

Protein tissue specificity

Kidney. Moderately expressed in aortic vascular smooth muscle and endothelial cells, and at a slightly higher level in the coronary vascular smooth muscle.

Protein sequence and domain

Belongs to the chloride channel (TC 2.A.49) family. ClC-5/CLCN5 subfamily.; Contains 2 CBS domains.

Protein post-translational modifications

Ubiquitinated by NEDD4L in the presence of albumin; which promotes endocytosis and proteasomal degradation.

Protein cellular localization

Golgi apparatus membrane ; Multi-pass membrane protein . Endosome membrane ; Multi-pass membrane protein . Cell membrane ; Multi-pass membrane protein .

Background

This gene encodes a member of the ClC family of chloride ion channels and ion transporters. The encoded protein is primarily localized to endosomal membranes and may function to facilitate albumin uptake by the renal proximal tubule. Mutations in this gene have been found in Dent disease and renal tubular disorders complicated by nephrolithiasis. Alternatively spliced transcript variants have been found for this gene.

Research area

All research areas>Channel Proteins>CLC
(View all antibody categories related to Channel Proteins)

Note

AntibodyPlus can customize CLCN5 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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