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Rabbit Polyclonal Cleaved-Caspase-2 p18 (G170) antibody (STJ90023)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, ELISA
Recommended dilution: WB 1:500-1:2000; ELISA 1:40000;
Recommended protocols: check protocols
Click or hover above images to see image description for Cleaved-Caspase-2 p18 (G170) Polyclonal Antibody.
Check alternative names for the antibodyExpand
CASP2 antibody, ICH1 antibody, NEDD2 antibody,|CASP2 antibody|ICH-1L antibody|ICH1 antibody|NEDD-2 antibody|NEDD2 antibody|Protease ICH-1 antibody|Anti-Caspase-2L antibody (ab2251)
SCBT cat No: sc-53928|sc-514472|sc-15379|sc-623|sc-136218|sc-626|sc-625|sc-5292|sc-8985|sc-56053|
Cleaved-Caspase-2 p18 (G170) Polyclonal Antibody
|Catalogue No.|| |
Cleaved-Caspase-2 p18 (G170) Polyclonal Antibody detects endogenous levels of fragment of activated Caspase-2 p18 protein resulting from cleavage adjacent to G170.
Synthesized peptide derived from Cleaved-Caspase-2 p18 (G170) at AA range 120-200
|Recommended dilution|| |
WB 1:500-1:2000; ELISA 1:40000;
|Molecular weight|| |
Cleaved-Caspase-2 p18 (G170) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Cleaved-Caspase-2 p18 (G170) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Caspase-2 antibody, CASP-2 antibody, Neural precursor cell expressed developmentally down-regulated protein 2 antibody, NEDD-2 antibody, Protease ICH-1 antibody
|Protein names|| |
Caspase-2 , CASP-2 , Neural precursor cell expressed developmentally down-regulated protein 2 , NEDD-2 , Protease ICH-1
|Protein function|| |
Involved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival. / Strict requirement for an Asp residue at P1, with 316-asp being essential for proteolytic activity and has a preferred cleavage sequence of Val-Asp-Val-Ala-Asp-, -.
|Protein tissue specificity|| |
Expressed at higher levels in the embryonic lung, liver and kidney than in the heart and brain. In adults, higher level expression is seen in the placenta, lung, kidney, and pancreas than in the heart, brain, liver and skeletal muscle.
|Protein sequence and domain|| |
Belongs to the peptidase C14A family. / Contains 1 CARD domain.
|Protein post-translational modifications|| |
The mature protease can process its own propeptide, but not that of other caspases.
AntibodyPlus can customize Cleaved-Caspase-2 p18 (G170) Antibody according to your requirement, including bulk product size,etc. Please contact email@example.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.
St John’s Laboratory Ltd.
|Product type|| |
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