Rabbit Polyclonal Cleaved-Caspase-2 p18 (T325) antibody (STJ90024)

$99.00$319.00

Reactivity: Human, Mouse, Rat
Applications: WB, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Cleaved-Caspase-2 p18 (T325) antibody (STJ90024)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, ELISA

Recommended dilution: WB 1:500-1:2000; ELISA 1:10000;

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Cleaved-Caspase-2 p18 (T325) Polyclonal Antibody.

Alternative names:

Check alternative names for the antibody

Expand

CASP2 antibody, ICH1 antibody, NEDD2 antibody,|CASP2 antibody|ICH-1L antibody|ICH1 antibody|NEDD-2 antibody|NEDD2 antibody|Protease ICH-1 antibody|Anti-Caspase-2L antibody (ab2251)
SCBT cat No: sc-53928|sc-514472|sc-15379|sc-623|sc-136218|sc-626|sc-625|sc-5292|sc-8985|sc-56053|

 

Name

Cleaved-Caspase-2 p18 (T325) Polyclonal Antibody

Catalogue No.

STJ90024

Reactivity

Human, Mouse, Rat

Specificity

Cleaved-Caspase-2 p18 (T325) Polyclonal Antibody detects endogenous levels of fragment of activated Caspase-2 p18 protein resulting from cleavage adjacent to T325.

Immunogen

Synthesized peptide derived from Cleaved-Caspase-2 p18 (T325) at AA range 250-330

Host

Rabbit

Applications

WB, ELISA

Recommended dilution

WB 1:500-1:2000; ELISA 1:10000;

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

22 kDa

Formulation

Cleaved-Caspase-2 p18 (T325) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

Cleaved-Caspase-2 p18 (T325) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Caspase-2 antibody, CASP-2 antibody, Neural precursor cell expressed developmentally down-regulated protein 2 antibody, NEDD-2 antibody, Protease ICH-1 antibody

Database links

Human UniProt/Swiss-Prot:P42575;Mouse UniPort/Swiss-Prot: P29594;Rat UniProt/Swiss-Port: P55215;Human Entrez Gene: 835;Mouse Entrez Gene: 12366;Rat Entrez Gene: Rn.1438

Protein names

Caspase-2 , CASP-2 , Neural precursor cell expressed developmentally down-regulated protein 2 , NEDD-2 , Protease ICH-1

Protein function

Involved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival. / Strict requirement for an Asp residue at P1, with 316-asp being essential for proteolytic activity and has a preferred cleavage sequence of Val-Asp-Val-Ala-Asp-, -.

Protein tissue specificity

Expressed at higher levels in the embryonic lung, liver and kidney than in the heart and brain. In adults, higher level expression is seen in the placenta, lung, kidney, and pancreas than in the heart, brain, liver and skeletal muscle.

Protein sequence and domain

Belongs to the peptidase C14A family. / Contains 1 CARD domain.

Protein post-translational modifications

The mature protease can process its own propeptide, but not that of other caspases.

Research area

All research areas>Tumor Suppressor/Apoptosis>Caspase
(View all antibody categories related to Tumor Suppressor/Apoptosis)

Note

AntibodyPlus can customize Cleaved-Caspase-2 p18 (T325) Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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