Rabbit Polyclonal Cleaved-Caspase-6 p18 (D179) antibody (STJ90007)

$99.00$319.00

Reactivity: Human, Rat
Applications: WB, IHC, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Cleaved-Caspase-6 p18 (D179) antibody (STJ90007)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, IHC, ELISA

Recommended dilution: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000;

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Cleaved-Caspase-6 p18 (D179) Polyclonal Antibody.

Alternative names:

Check alternative names for the antibody

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CASP6 antibody, MCH2 antibody,|Apoptotic protease Mch-2 antibody|Caspase-6 subunit p11 antibody|Mch2 antibody|OTTHUMP00000162742 antibody|OTTHUMP00000162743 antibody|Anti-Caspase-6 antibody [EPR18043] (ab185645)
SCBT cat No: sc-81652|sc-81653|sc-56060|sc-56061|sc-73539|sc-1231|sc-1230|sc-377393|sc-15380|sc-130714|sc-1232|sc-81654|sc-56063|

 

Name

Cleaved-Caspase-6 p18 (D179) Polyclonal Antibody

Catalogue No.

STJ90007

Reactivity

Human, Rat

Specificity

Cleaved-Caspase-6 p18 (D179) Polyclonal Antibody detects endogenous levels of fragment of activated Caspase-6 p18 protein resulting from cleavage adjacent to D179.

Immunogen

Synthesized peptide derived from Cleaved-Caspase-6 p18 (D179) at AA range 90-170

Host

Rabbit

Applications

WB, IHC, ELISA

Recommended dilution

WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000;

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

20/35 kDa

Formulation

Cleaved-Caspase-6 p18 (D179) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

Cleaved-Caspase-6 p18 (D179) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Caspase-6 antibody, CASP-6 antibody, Apoptotic protease Mch-2 antibody

Database links

Human UniProt/Swiss-Prot:P55212;Mouse UniPort/Swiss-Prot: O08738;Rat UniProt/Swiss-Port: Q6AZ23;Human Entrez Gene: 839;Mouse Entrez Gene: 12368;Rat Entrez Gene: Rn.88160

Protein names

Caspase-6 , CASP-6 , Apoptotic protease Mch-2

Protein function

Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death. / Strict requirement for Asp at position P1 and has a preferred cleavage sequence of Val-Glu-His-Asp-, -. / Activation is suppressed by phosphorylation at Ser-257.

Protein sequence and domain

Belongs to the peptidase C14A family.

Protein post-translational modifications

Cleavages by caspase-3, caspase-8 or -10 generate the two active subunits.

Protein cellular localization

Cytoplasm

Research area

All research areas>Tumor Suppressor/Apoptosis>Caspase
(View all antibody categories related to Tumor Suppressor/Apoptosis)

Note

AntibodyPlus can customize Cleaved-Caspase-6 p18 (D179) Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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