Rabbit Polyclonal Cleaved-Caspase-7 (S199) antibody (STJ90009)

$99.00$319.00

Reactivity: Human, Mouse
Applications: WB, IHC, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

Clear
-$50 as credit for submitting review for primary antibody
Shipping notice:
Product will be delivered in 6 to 8 Business Days

Rabbit Polyclonal Cleaved-Caspase-7 (S199) antibody (STJ90009)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, IHC, ELISA

Recommended dilution: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000;

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Cleaved-Caspase-7 (S199) Polyclonal Antibody.

Alternative names:

Check alternative names for the antibody

Expand

CASP7 antibody, MCH3 antibody,|Apoptotic protease Mch-3 antibody|Caspase-7 subunit p11 antibody|Caspase7 antibody|CMH 1 antibody|CMH-1 antibody|CMH1 antibody|ICE LAP3 antibody|ICE-LAP3 antibody|ICE-like apoptotic protease 3 antibody|LICE2 antibody|MCH3 antibody|Anti-Caspase-7 antibody [E22] (ab32522)
SCBT cat No: sc-81654|sc-56063|sc-81655|sc-73424|sc-135858|sc-81660|sc-56066|sc-56067|sc-6138|sc-56068|sc-365034|sc-271747|sc-28295|sc-133248|sc-133247|sc-33773|sc-8510|

 

Name

Cleaved-Caspase-7 (S199) Polyclonal Antibody

Catalogue No.

STJ90009

Reactivity

Human, Mouse

Specificity

Cleaved-Caspase-7 (S199) Polyclonal Antibody detects endogenous levels of fragment of activated Caspase-7 protein resulting from cleavage adjacent to S199.

Immunogen

Synthesized peptide derived from Cleaved-Caspase-7 (S199) at AA range 150-230

Host

Rabbit

Applications

WB, IHC, ELISA

Recommended dilution

WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000;

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

20 kDa

Formulation

Cleaved-Caspase-7 (S199) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

Cleaved-Caspase-7 (S199) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Caspase-7 antibody, CASP-7 antibody, Apoptotic protease Mch-3 antibody, CMH-1 antibody, ICE-like apoptotic protease 3 antibody, ICE-LAP3 antibody

Database links

Human UniProt/Swiss-Prot:P55210;Mouse UniPort/Swiss-Prot: P97864;Rat UniProt/Swiss-Port: O88550;Human Entrez Gene: 840;Mouse Entrez Gene: 12369;Rat Entrez Gene: Rn.53995

Protein names

Caspase-7 , CASP-7 , Apoptotic protease Mch-3 , CMH-1 , ICE-like apoptotic protease 3 , ICE-LAP3

Protein function

Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a ‘216-Asp-, -Gly-217’ bond. Overexpression promotes programmed cell death. / Strict requirement for an Asp residue at position P1 and has a preferred cleavage sequence of Asp-Glu-Val-Asp-, -. / Inhibited by isatin sulfonamides.

Protein tissue specificity

Highly expressed in lung, skeletal muscle, liver, kidney, spleen and heart, and moderately in testis. No expression in the brain.

Protein sequence and domain

Belongs to the peptidase C14A family.

Protein post-translational modifications

Cleavages by granzyme B or caspase-10 generate the two active subunits. Propeptide domains can also be cleaved efficiently by caspase-3. Active heterodimers between the small subunit of caspase-7 and the large subunit of caspase-3, and vice versa, also occur.

Protein cellular localization

Cytoplasm

Research area

All research areas>Tumor Suppressor/Apoptosis>Caspase
(View all antibody categories related to Tumor Suppressor/Apoptosis)

Note

AntibodyPlus can customize Cleaved-Caspase-7 (S199) Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

Reviews


There are no reviews yet.

Only logged in customers who have purchased this product may leave a review

There are no reviews for this product yet.
By submitting a review, get following benefits:

1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!

view database submit reviews

There is no extra validation for this product yet.
Check other extra validated antibodies below:



Welcome to AntibodyPlus!