Rabbit Polyclonal Cleaved-Cathepsin A 32k (R326) antibody (STJ90033)

$99.00$319.00

Reactivity: Human, Mouse
Applications: WB, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

Clear
-$50 as credit for submitting review for primary antibody
Shipping notice:
Product will be delivered in 6 to 8 Business Days

Rabbit Polyclonal Cleaved-Cathepsin A 32k (R326) antibody (STJ90033)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, ELISA

Recommended dilution: WB 1:500-1:2000; ELISA 1:10000;

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Cleaved-Cathepsin A 32k (R326) Polyclonal Antibody.

Alternative names:

Check alternative names for the antibody

Expand

CTSA antibody, PPGB antibody,|beta galactosidase 2 antibody|BETA GALACTOSIDASE PROTECTIVE PROTEIN antibody|beta-galactosidase 2 antibody|beta-galactosidase protective protein antibody|betagalactosidase 2 antibody|Carboxypeptidase C antibody|Carboxypeptidase L antibody|carboxypeptidase Y-like kininase antibody|Cathepsin A antibody|Ctsa antibody|deamidase antibody|EC 3.4.16.5 antibody|Glactosialidosis antibody|GLB2 antibody|Goldberg Syndrome antibody|GSL antibody|lysosomal carboxypeptidase A antibody|Lysosomal protective protein 20 kDa chain antibody|Lysosomal protective protein antibody|Lysosomal protective protein deficiency antibody|NEURAMINIDASE BETA GALACTOSIDASE EXPRESSION; NGBE antibody|Neuraminidase deficiency with beta-galactosidase deficiency antibody|NGBE antibody|OTTHUMP00000031778 antibody|OTTHUMP00000031781 antibody|PPCA antibody|PPCA deficiency antibody|PPGB antibody|PPGB_HUMAN antibody|Protective protein cathepsin A antibody|Protective protein for beta galactosidase antibody|Protective protein for beta-galactosidase antibody|Protective protein/cathepsin A deficiency antibody|urinary kininase antibody|Anti-Protective protein/Cathepsin A (PPCA) antibody [EPR10435] (ab184553)
SCBT cat No: sc-73766|sc-26049|sc-26050|sc-292167|

 

Name

Cleaved-Cathepsin A 32k (R326) Polyclonal Antibody

Catalogue No.

STJ90033

Reactivity

Human, Mouse

Specificity

Cleaved-Cathepsin A 32k (R326) Polyclonal Antibody detects endogenous levels of fragment of activated Cathepsin A 32k protein resulting from cleavage adjacent to R326.

Immunogen

Synthesized peptide derived from Cleaved-Cathepsin A 32k (R326) at AA range 250-330

Host

Rabbit

Applications

WB, ELISA

Recommended dilution

WB 1:500-1:2000; ELISA 1:10000;

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

33 kDa

Formulation

Cleaved-Cathepsin A 32k (R326) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

Cleaved-Cathepsin A 32k (R326) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Lysosomal protective protein antibody, Carboxypeptidase C antibody, Carboxypeptidase L antibody, Cathepsin A antibody, Protective protein cathepsin A antibody, PPCA antibody, Protective protein for beta-galactosidase antibody

Database links

Human UniProt/Swiss-Prot:P10619;Mouse UniPort/Swiss-Prot: P16675;Human Entrez Gene: 5476;Mouse Entrez Gene: 19025;Rat Entrez Gene: Rn.104631

Protein names

Lysosomal protective protein , Carboxypeptidase C , Carboxypeptidase L , Cathepsin A , Protective protein cathepsin A , PPCA , Protective protein for beta-galactosidase

Protein function

Protective protein appears to be essential for both the activity of beta-galactosidase and neuraminidase, it associates with these enzymes and exerts a protective function necessary for their stability and activity. This protein is also a carboxypeptidase and can deamidate tachykinins. / Release of a C-terminal amino acid with broad specificity.

Involvement in disease

Galactosialidosis (GSL) [MIM:256540]: A lysosomal storage disease associated with a combined deficiency of beta-galactosidase and neuraminidase, secondary to a defect in cathepsin A. All patients have clinical manifestations typical of a lysosomal disorder, such as coarse facies, cherry red spots, vertebral changes, foam cells in the bone marrow, and vacuolated lymphocytes. Three phenotypic subtypes are recognized. The early infantile form is associated with fetal hydrops, edema, ascites, visceromegaly, skeletal dysplasia, and early death. The late infantile type is characterized by hepatosplenomegaly, growth retardation, cardiac involvement, and a normal or mildly affected mental state. The juvenile/adult form is characterized by myoclonus, ataxia, angiokeratoma, mental retardation, neurologic deterioration, absence of visceromegaly, and long survival. . Note: The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the peptidase S10 family.

Protein cellular localization

Lysosome

Research area

All research areas>Synthesis and Degradation>Cathepsin
(View all antibody categories related to Synthesis and Degradation)

Note

AntibodyPlus can customize Cleaved-Cathepsin A 32k (R326) Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

Reviews


There are no reviews yet.

Only logged in customers who have purchased this product may leave a review

There are no reviews for this product yet.
By submitting a review, get following benefits:

1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!

view database submit reviews

There is no extra validation for this product yet.
Check other extra validated antibodies below:



Welcome to AntibodyPlus!