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Rabbit Polyclonal Cleaved-Cathepsin D HC (L169) antibody (STJ90036)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, ELISA
Recommended dilution: WB 1:500-1:2000; ELISA 1:40000;
Recommended protocols: check protocols
Click or hover above images to see image description for Cleaved-Cathepsin D HC (L169) Polyclonal Antibody.
Check alternative names for the antibodyExpand
CTSD antibody, CPSD antibody,|CatD antibody|CATD_HUMAN antibody|Cathepsin D antibody|Cathepsin D heavy chain antibody|CD antibody|Ceroid lipofuscinosis neuronal 10 antibody|CLN10 antibody|CPSD antibody|ctsd antibody|Epididymis secretory sperm binding protein Li 130P antibody|HEL S 130P antibody|Lysosomal aspartyl peptidase antibody|Lysosomal aspartyl protease antibody|MGC2311 antibody|Anti-Cathepsin D antibody [CTD-19] (ab6313)
SCBT cat No: sc-136282|sc-53927|sc-6486|sc-377124|sc-377299|sc-13148|sc-374381|sc-6494|sc-10725|sc-6488|sc-6487|
Cleaved-Cathepsin D HC (L169) Polyclonal Antibody
|Catalogue No.|| |
Cleaved-Cathepsin D HC (L169) Polyclonal Antibody detects endogenous levels of fragment of activated Cathepsin D HC protein resulting from cleavage adjacent to L169.
Synthesized peptide derived from Cleaved-Cathepsin D HC (L169) at AA range 120-200
|Recommended dilution|| |
WB 1:500-1:2000; ELISA 1:40000;
|Molecular weight|| |
Cleaved-Cathepsin D HC (L169) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Cleaved-Cathepsin D HC (L169) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Cathepsin D antibody, antibody
|Protein names|| |
Cathepsin D ,
|Protein function|| |
Acid protease active in intracellular protein breakdown. Involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease. / Specificity similar to, but narrower than, that of pepsin A. Does not cleave the 4-Gln-, -His-5 bond in B chain of insulin.
|Protein tissue specificity|| |
Expressed in the aorta extrcellular space (at protein level).
|Involvement in disease|| |
Ceroid lipofuscinosis, neuronal, 10 (CLN10) [MIM:610127]: A form of neuronal ceroid lipofuscinosis with onset at birth or early childhood. Neuronal ceroid lipofuscinoses are progressive neurodegenerative, lysosomal storage diseases characterized by intracellular accumulation of autofluorescent liposomal material, and clinically by seizures, dementia, visual loss, and/or cerebral atrophy. . Note: The disease is caused by mutations affecting the gene represented in this entry.
|Protein sequence and domain|| |
Belongs to the peptidase A1 family. / Contains 1 peptidase A1 domain.
|Protein post-translational modifications|| |
N- and O-glycosylated.
|Protein cellular localization|| |
Lysosome / Melanosome / Secreted > extracellular space
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St John’s Laboratory Ltd.
|Product type|| |
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