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Rabbit Polyclonal Cleaved-CD97alpha (L530) antibody (STJ90046)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, ELISA
Recommended dilution: WB 1:500-1:2000; ELISA 1:5000;
Recommended protocols: check protocols
Click or hover above images to see image description for Cleaved-CD97alpha (L530) Polyclonal Antibody.
Check alternative names for the antibodyExpand
CD97 antibody,|ADGRE5 antibody|Adhesion G protein-coupled receptor E5 antibody|CD 97 antibody|CD_antigen=CD97 antibody|CD97 antibody|CD97 antigen antibody|CD97 antigen subunit beta antibody|CD97 molecule antibody|CD97_HUMAN antibody|Leukocyte antigen CD97 antibody|Seven span transmembrane protein antibody|Seven transmembrane helix receptor antibody|Seven transmembrane heterodimeric receptor associated with inflammation antibody|TM7LN 1 antibody|TM7LN1 antibody|Anti-CD97 antibody [EPR4427] (ab108368)
SCBT cat No: sc-26105|sc-166852|sc-98576|
Cleaved-CD97alpha (L530) Polyclonal Antibody
|Catalogue No.|| |
Cleaved-CD97alpha (L530) Polyclonal Antibody detects endogenous levels of fragment of activated CD97alpha protein resulting from cleavage adjacent to L530.
Synthesized peptide derived from Cleaved-CD97alpha (L530) at AA range 450-530
|Recommended dilution|| |
WB 1:500-1:2000; ELISA 1:5000;
|Molecular weight|| |
Cleaved-CD97alpha (L530) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Cleaved-CD97alpha (L530) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
CD97 antigen antibody, Leukocyte antigen CD97 antibody, CD antigen CD97 antibody
|Protein names|| |
CD97 antigen , Leukocyte antigen CD97 , CD antigen CD97
|Protein function|| |
Receptor potentially involved in both adhesion and signaling processes early after leukocyte activation. Plays an essential role in leukocyte migration (By similarity).
|Protein tissue specificity|| |
Broadly expressed, found on most hematopoietic cells, including activated lymphocytes, monocytes, macrophages, dendritic cells, and granulocytes. Expressed also abundantly by smooth muscle cells. Expressed in thyroid, colorectal, gastric, esophageal and pancreatic carcinomas too. Expression are increased under inflammatory conditions in the CNS of multiple sclerosis and in synovial tissue of patients with rheumatoid arthritis. Increased expression of CD97 in the synovium is accompanied by detectable levels of soluble CD97 in the synovial fluid.
|Protein sequence and domain|| |
The first two EGF domains mediate the interaction with DAF. A third tandemly arranged EGF domain is necessary for the structural integrity of the binding region. / Binding to chondroitin sulfate is mediated by the fourth EGF domain. / Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. / Contains 5 EGF-like domains. / Contains 1 GPS domain.
|Protein post-translational modifications|| |
Proteolytically cleaved into 2 subunits, an extracellular alpha subunit and a seven-transmembrane subunit.
|Protein cellular localization|| |
Cell membrane; Multi-pass membrane protein / Secreted > extracellular space
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St John’s Laboratory Ltd.
|Product type|| |
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