Rabbit Polyclonal Cleaved-Factor Xa activated HC (I235) antibody (STJ90082)

$99.00$319.00

Reactivity: Human, Mouse, Rat
Applications: WB, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Cleaved-Factor Xa activated HC (I235) antibody (STJ90082)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, ELISA

Recommended dilution: WB 1:500-1:2000; ELISA 1:20000;

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Cleaved-Factor Xa activated HC (I235) Polyclonal Antibody.

Alternative names:

Check alternative names for the antibody

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F10 antibody,|Activated factor Xa heavy chain antibody|Coagulation factor X antibody|F10 antibody|FA10_HUMAN antibody|factor Xa antibody|FX antibody|FXA antibody|Prothrombinase antibody|Stuart factor antibody|Stuart Prower factor antibody|Stuart-Prower factor antibody|Anti-Factor X antibody (ab79929)
SCBT cat No: sc-101370|sc-69654|sc-65954|sc-20673|

 

Name

Cleaved-Factor Xa activated HC (I235) Polyclonal Antibody

Catalogue No.

STJ90082

Reactivity

Human, Mouse, Rat

Specificity

Cleaved-Factor Xa activated HC (I235) Polyclonal Antibody detects endogenous levels of fragment of activated Factor Xa activated HC protein resulting from cleavage adjacent to I235.

Immunogen

Synthesized peptide derived from Cleaved-Factor Xa activated HC (I235) at AA range 190-270

Host

Rabbit

Applications

WB, ELISA

Recommended dilution

WB 1:500-1:2000; ELISA 1:20000;

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

30 kDa

Formulation

Cleaved-Factor Xa activated HC (I235) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

Cleaved-Factor Xa activated HC (I235) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Coagulation factor X antibody, Stuart factor antibody, Stuart-Prower factor antibody

Database links

Human UniProt/Swiss-Prot:P00742;Mouse UniPort/Swiss-Prot: O88947;Rat UniProt/Swiss-Port: Q63207;Human Entrez Gene: 2159;Mouse Entrez Gene: 14058;Rat Entrez Gene: Rn.21393

Protein names

Coagulation factor X , Stuart factor , Stuart-Prower factor

Protein function

Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting. / Selective cleavage of Arg-, -Thr and then Arg-, -Ile bonds in prothrombin to form thrombin. / Inhibited by SERPINA5 and SERPINA10.

Protein tissue specificity

Plasma; synthesized in the liver.

Involvement in disease

Factor X deficiency (FA10D) [MIM:227600]: A hemorrhagic disease with variable presentation. Affected individuals can manifest prolonged nasal and mucosal hemorrhage, menorrhagia, hematuria, and occasionally hemarthrosis. Some patients do not have clinical bleeding diathesis. . Note: The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the peptidase S1 family. / Contains 2 EGF-like domains. / Contains 1 Gla (gamma-carboxy-glutamate) domain. / Contains 1 peptidase S1 domain.

Protein post-translational modifications

The vitamin K-dependent, enzymatic carboxylation of some glutamate residues allows the modified protein to bind calcium. / N- and O-glycosylated. O-glycosylated with core 1 or possibly core 8 glycans. / The activation peptide is cleaved by factor IXa (in the intrinsic pathway), or by factor VIIa (in the extrinsic pathway). / The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains.

Protein cellular localization

Secreted

Research area

All research areas>Signaling Intermediates>Coagulation Factor
(View all antibody categories related to Signaling Intermediates)

Note

AntibodyPlus can customize Cleaved-Factor Xa activated HC (I235) Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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