Rabbit Polyclonal Cleaved-MMP-15 (Y132) antibody (STJ90061)

$99.00$319.00

Reactivity: Human, Monkey
Applications: WB, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Cleaved-MMP-15 (Y132) antibody (STJ90061)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, ELISA

Recommended dilution: WB 1:500-1:2000; ELISA 1:10000;

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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MMP15 antibody,|AI503551 antibody|Matrix metallopeptidase 15 membrane inserted antibody|Matrix metalloproteinase 15 antibody|Matrix metalloproteinase-15 antibody|Membrane type 2 matrix metalloproteinase antibody|Membrane type matrix metalloproteinase 2 antibody|Membrane-type matrix metalloproteinase 2 antibody|Membrane-type-2 matrix metalloproteinase antibody|MMP 15 antibody|MMP-15 antibody|MMP15 antibody|MMP15_HUMAN antibody|MT MMP 2 antibody|MT-MMP 2 antibody|MT2 MMP antibody|MT2-MMP antibody|MT2MMP antibody|MTMMP 2 antibody|MTMMP2 antibody|SMCP 2 antibody|SMCP-2 antibody|SMCP2 antibody|Anti-MMP15 antibody – N-terminal (ab135562)
SCBT cat No: sc-8844|sc-101452|sc-80213|

 

Name

Cleaved-MMP-15 (Y132) Polyclonal Antibody

Catalogue No.

STJ90061

Reactivity

Human, Monkey

Specificity

Cleaved-MMP-15 (Y132) Polyclonal Antibody detects endogenous levels of fragment of activated MMP-15 protein resulting from cleavage adjacent to Y132.

Immunogen

Synthesized peptide derived from Cleaved-MMP-15 (Y132) at AA range 90-170

Host

Rabbit

Applications

WB, ELISA

Recommended dilution

WB 1:500-1:2000; ELISA 1:10000;

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

61 kDa

Formulation

Cleaved-MMP-15 (Y132) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

Cleaved-MMP-15 (Y132) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Matrix metalloproteinase-15 antibody, MMP-15 antibody, Membrane-type matrix metalloproteinase 2 antibody, MT-MMP 2 antibody, MTMMP2 antibody, Membrane-type-2 matrix metalloproteinase antibody, MT2-MMP antibody, MT2MMP antibody, SMCP-2 antibody

Database links

Human UniProt/Swiss-Prot:P51511;Mouse UniPort/Swiss-Prot: O54732;Rat UniProt/Swiss-Port: D3ZCG5;Human Entrez Gene: 4324;Mouse Entrez Gene: 17388;Rat Entrez Gene: Rn.165433

Protein names

Matrix metalloproteinase-15 , MMP-15 , Membrane-type matrix metalloproteinase 2 , MT-MMP 2 , MTMMP2 , Membrane-type-2 matrix metalloproteinase , MT2-MMP , MT2MMP , SMCP-2

Protein function

Endopeptidase that degrades various components of the extracellular matrix. May activate progelatinase A. / Zn2+ / Ca2+

Protein tissue specificity

Appeared to be synthesized preferentially in liver, placenta, testis, colon and intestine. Substantial amounts are also detected in pancreas, kidney, lung, heart and skeletal muscle.

Protein sequence and domain

The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme. / Belongs to the peptidase M10A family. / Contains 4 hemopexin repeats.

Protein post-translational modifications

The precursor is cleaved by a furin endopeptidase.

Protein cellular localization

Membrane

Research area

All research areas>Synthesis and Degradation>MT-MMP
(View all antibody categories related to Synthesis and Degradation)

Note

AntibodyPlus can customize Cleaved-MMP-15 (Y132) Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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