No products in the cart.
Rabbit Polyclonal Cleaved-MMP-17 (Q129) antibody (STJ90062)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, ELISA
Recommended dilution: WB 1:500-1:2000; ELISA 1:10000;
Recommended protocols: check protocols
Click or hover above images to see image description for Cleaved-MMP-17 (Q129) Polyclonal Antibody.
Check alternative names for the antibodyExpand
MMP17 antibody, MT4MMP antibody,|Matrix metalloproteinase 17 antibody|Matrix metalloproteinase 17 membrane inserted antibody|Matrix metalloproteinase-17 antibody|Membrane type 4 matrix metalloproteinase antibody|Membrane type matrix metalloproteinase 4 antibody|Membrane-type matrix metalloproteinase 4 antibody|Membrane-type-4 matrix metalloproteinase antibody|MMP 17 antibody|MMP-17 antibody|Mmp17 antibody|MMP17_HUMAN antibody|MT MMP 4 antibody|MT MMP4 antibody|MT-MMP 4 antibody|MT4 MMP antibody|MT4-MMP antibody|MT4MMP antibody|MTMMP 4 antibody|MTMMP4 antibody|Anti-MMP17 antibody [EP1270Y] (ab51075)
SCBT cat No: sc-8847|sc-13972|
Cleaved-MMP-17 (Q129) Polyclonal Antibody
|Catalogue No.|| |
Cleaved-MMP-17 (Q129) Polyclonal Antibody detects endogenous levels of fragment of activated MMP-17 protein resulting from cleavage adjacent to Q129.
Synthesized peptide derived from Cleaved-MMP-17 (Q129) at AA range 80-160
|Recommended dilution|| |
WB 1:500-1:2000; ELISA 1:10000;
|Molecular weight|| |
Cleaved-MMP-17 (Q129) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Cleaved-MMP-17 (Q129) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Matrix metalloproteinase-17 antibody, MMP-17 antibody, Membrane-type matrix metalloproteinase 4 antibody, MT-MMP 4 antibody, MTMMP4 antibody, Membrane-type-4 matrix metalloproteinase antibody, MT4-MMP antibody, MT4MMP antibody
|Protein names|| |
Matrix metalloproteinase-17 , MMP-17 , Membrane-type matrix metalloproteinase 4 , MT-MMP 4 , MTMMP4 , Membrane-type-4 matrix metalloproteinase , MT4-MMP , MT4MMP
|Protein function|| |
Endopeptidase that degrades various components of the extracellular matrix, such as fibrin. May be involved in the activation of membrane-bound precursors of growth factors or inflammatory mediators, such as tumor necrosis factor-alpha. May also be involved in tumoral process. Not obvious if able to proteolytically activate progelatinase A. Does not hydrolyze collagen types I, II, III, IV and V, gelatin, fibronectin, laminin, decorin nor alpha1-antitrypsin. / Cleaves pro-TNF-alpha at the 74-Ala-, -Gln-75 site. / Zn2+ / Ca2+
|Protein tissue specificity|| |
Expressed in brain, leukocytes, colon, ovary testis and breast cancer. Expressed also in many transformed and non-transformed cell types.
|Protein sequence and domain|| |
The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme. / Belongs to the peptidase M10A family. / Contains 4 hemopexin repeats.
|Protein post-translational modifications|| |
The precursor is cleaved by a furin endopeptidase.
|Protein cellular localization|| |
Cell membrane; Lipid-anchor > GPI-anchor; Extracellular side / Secreted > extracellular space > extracellular matrix
AntibodyPlus can customize Cleaved-MMP-17 (Q129) Antibody according to your requirement, including bulk product size,etc. Please contact email@example.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.
St John’s Laboratory Ltd.
|Product type|| |
There are no reviews for this product yet.
By submitting a review, get following benefits:
1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!
There is no extra validation for this product yet.
Check other extra validated antibodies below: