Rabbit Polyclonal Cleaved-MMP-3 (F100) antibody (STJ90065)


Reactivity: Human
Applications: WB, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Cleaved-MMP-3 (F100) antibody (STJ90065)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, ELISA

Recommended dilution: WB 1:500-1:2000; ELISA 1:20000;

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Cleaved-MMP-3 (F100) Polyclonal Antibody.

Alternative names:

Check alternative names for the antibody


MMP3 antibody, STMY1 antibody,|CHDS6 antibody|Matrix metalloproteinase 3 antibody|Matrix metalloproteinase-3 antibody|MGC126102 antibody|MGC126103 antibody|MGC126104 antibody|MMP 3 antibody|MMP-3 antibody|MMP3 antibody|MMP3_HUMAN antibody|Proteoglycanase antibody|SL-1 antibody|SL1 antibody|STMY antibody|STMY1 antibody|STR1 antibody|Stromelysin 1 antibody|Stromelysin-1 antibody|Transin 1 antibody|Transin-1 antibody|Anti-MMP3 antibody (ab53015)
SCBT cat No: sc-31074|



Cleaved-MMP-3 (F100) Polyclonal Antibody

Catalogue No.





Cleaved-MMP-3 (F100) Polyclonal Antibody detects endogenous levels of fragment of activated MMP-3 protein resulting from cleavage adjacent to F100.


Synthesized peptide derived from Cleaved-MMP-3 (F100) at AA range 50-130





Recommended dilution

WB 1:500-1:2000; ELISA 1:20000;







Molecular weight

43 kDa


Cleaved-MMP-3 (F100) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.


1 mg/ml


Cleaved-MMP-3 (F100) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.


-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Stromelysin-1 antibody, SL-1 antibody, Matrix metalloproteinase-3 antibody, MMP-3 antibody, Transin-1 antibody

Database links

Human UniProt/Swiss-Prot:P08254;Mouse UniPort/Swiss-Prot: P28862;Human Entrez Gene: 4314;Mouse Entrez Gene: 17392;Rat Entrez Gene: Rn.32086

Protein names

Stromelysin-1 , SL-1 , Matrix metalloproteinase-3 , MMP-3 , Transin-1

Protein function

Can degrade fibronectin, laminin, gelatins of type I, III, IV, and V; collagens III, IV, X, and IX, and cartilage proteoglycans. Activates procollagenase. / Preferential cleavage where P1′, P2′ and P3′ are hydrophobic residues. / Ca2+ / Zn2+

Involvement in disease

Coronary heart disease 6 (CHDS6) [MIM:614466]: A multifactorial disease characterized by an imbalance between myocardial functional requirements and the capacity of the coronary vessels to supply sufficient blood flow. Decreased capacity of the coronary vessels is often associated with thickening and loss of elasticity of the coronary arteries. . Note: Disease susceptibility is associated with variations affecting the gene represented in this entry. A polymorphism in the MMP3 promoter region is associated with the risk of coronary heart disease and myocardial infarction, due to lower MMP3 proteolytic activity and higher extracellular matrix deposition in atherosclerotic lesions.

Protein sequence and domain

The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme. / Belongs to the peptidase M10A family. / Contains 4 hemopexin repeats.

Protein cellular localization

Secreted > extracellular space > extracellular matrix

Research area

All research areas>Synthesis and Degradation>MMP
(View all antibody categories related to Synthesis and Degradation)


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St John’s Laboratory Ltd.

Product type

Primary antibody


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