Rabbit Polyclonal Cleaved-Plasma Kallikrein HC (R390) antibody (STJ90101)

$99.00$319.00

Reactivity: Human
Applications: WB, IHC, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Rabbit Polyclonal Cleaved-Plasma Kallikrein HC (R390) antibody (STJ90101)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, IHC, ELISA

Recommended dilution: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000;

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Cleaved-Plasma Kallikrein HC (R390) Polyclonal Antibody.

Alternative names:

Check alternative names for the antibody

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KLKB1 antibody, KLK3 antibody,|Fletcher factor antibody|kallikrein B plasma antibody|Kallikrein B plasma (Fletcher factor) 1 antibody|Kallikrein B, plasma 1 antibody|Kininogenin antibody|KLK3 antibody|KLKB1 antibody|KLKB1_HUMAN antibody|Plasma kallikrein antibody|Plasma kallikrein B1 antibody|Plasma kallikrein light chain antibody|Plasma prekallikrein antibody|PPK antibody|Prekallikrein antibody|Anti-Plasma Kallikrein 1B antibody [13G11] (ab1006)
SCBT cat No: sc-25799|sc-59581|sc-80524|sc-23915|

 

Name

Cleaved-Plasma Kallikrein HC (R390) Polyclonal Antibody

Catalogue No.

STJ90101

Reactivity

Human

Specificity

Cleaved-Plasma Kallikrein HC (R390) Polyclonal Antibody detects endogenous levels of fragment of activated Plasma Kallikrein HC protein resulting from cleavage adjacent to R390.

Immunogen

Synthesized peptide derived from Cleaved-Plasma Kallikrein HC (R390) at AA range 310-390

Host

Rabbit

Applications

WB, IHC, ELISA

Recommended dilution

WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000;

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

45 kDa

Formulation

Cleaved-Plasma Kallikrein HC (R390) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

Cleaved-Plasma Kallikrein HC (R390) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Plasma kallikrein antibody, Fletcher factor antibody, Kininogenin antibody, Plasma prekallikrein antibody, PKK antibody

Database links

Human UniProt/Swiss-Prot:P03952;Mouse UniPort/Swiss-Prot: P26262;Rat UniProt/Swiss-Port: Q5FVS2;Human Entrez Gene: 3818;Mouse Entrez Gene: 16621;Rat Entrez Gene: Rn.9880

Protein names

Plasma kallikrein , Fletcher factor , Kininogenin , Plasma prekallikrein , PKK

Protein function

The enzyme cleaves Lys-Arg and Arg-Ser bonds. It activates, in a reciprocal reaction, factor XII after its binding to a negatively charged surface. It also releases bradykinin from HMW kininogen and may also play a role in the renin-angiotensin system by converting prorenin into renin. / Cleaves selectively Arg-, -Xaa and Lys-, -Xaa bonds, including Lys-, -Arg and Arg-, -Ser bonds in (human) kininogen to release bradykinin. / Inhibited by SERPINA5.

Involvement in disease

Prekallikrein deficiency (PKK deficiency) [MIM:612423]: This disorder is a blood coagulation defect. . Note: The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the peptidase S1 family. Plasma kallikrein subfamily. / Contains 4 apple domains. / Contains 1 peptidase S1 domain.

Protein cellular localization

Secreted

Note

AntibodyPlus can customize Cleaved-Plasma Kallikrein HC (R390) Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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