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Rabbit Polyclonal Cleaved-Thrombin R (S42) antibody (STJ90103)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, ELISA
Recommended dilution: WB 1:500-1:2000; ELISA 1:20000;
Recommended protocols: check protocols
Click or hover above images to see image description for Cleaved-Thrombin R (S42) Polyclonal Antibody.
Check alternative names for the antibodyExpand
F2R antibody, CF2R antibody, PAR1 antibody, TR antibody,|CF2R antibody|Coagulation factor II (thrombin) receptor antibody|Coagulation factor II receptor antibody|F2R antibody|HTR antibody|PAR 1 antibody|PAR-1 antibody|PAR1 antibody|PAR1_HUMAN antibody|Protease activated receptor 1 antibody|Proteinase activated receptor 1 antibody|Proteinase-activated receptor 1 antibody|Thrombin receptor antibody|TR antibody|Anti-Thrombin Receptor antibody (ab32611)
SCBT cat No: To be updated
Cleaved-Thrombin R (S42) Polyclonal Antibody
|Catalogue No.|| |
Cleaved-Thrombin R (S42) Polyclonal Antibody detects endogenous levels of fragment of activated Thrombin R protein resulting from cleavage adjacent to S42.
Synthesized peptide derived from Cleaved-Thrombin R (S42) at AA range 40-120
|Recommended dilution|| |
WB 1:500-1:2000; ELISA 1:20000;
|Molecular weight|| |
Cleaved-Thrombin R (S42) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Cleaved-Thrombin R (S42) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Proteinase-activated receptor 1 antibody, PAR-1 antibody, Coagulation factor II receptor antibody, Thrombin receptor antibody
|Protein names|| |
Proteinase-activated receptor 1 , PAR-1 , Coagulation factor II receptor , Thrombin receptor
|Protein function|| |
High affinity receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation and in vascular development.
|Protein tissue specificity|| |
Platelets and vascular endothelial cells.
|Protein sequence and domain|| |
The cleaved signal peptide may not be degraded and may function as an intracellular angiogenesis inhibitor peptide known as parstatin. / Belongs to the G-protein coupled receptor 1 family.
|Protein post-translational modifications|| |
A proteolytic cleavage generates a new N-terminus that functions as a tethered ligand. / Phosphorylated in the C-terminal tail; probably mediating desensitization prior to the uncoupling and internalization of the receptor.
|Protein cellular localization|| |
Cell membrane; Multi-pass membrane protein
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St John’s Laboratory Ltd.
|Product type|| |
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