Rabbit Polyclonal Cleaved-Thrombin R (S42) antibody (STJ90103)

$99.00$319.00

Reactivity: Human
Applications: WB, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

Clear
-$50 as credit for submitting review for primary antibody
Shipping notice:
Product will be delivered in 6 to 8 Business Days

Rabbit Polyclonal Cleaved-Thrombin R (S42) antibody (STJ90103)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, ELISA

Recommended dilution: WB 1:500-1:2000; ELISA 1:20000;

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Cleaved-Thrombin R (S42) Polyclonal Antibody.

Alternative names:

Check alternative names for the antibody

Expand

F2R antibody, CF2R antibody, PAR1 antibody, TR antibody,|CF2R antibody|Coagulation factor II (thrombin) receptor antibody|Coagulation factor II receptor antibody|F2R antibody|HTR antibody|PAR 1 antibody|PAR-1 antibody|PAR1 antibody|PAR1_HUMAN antibody|Protease activated receptor 1 antibody|Proteinase activated receptor 1 antibody|Proteinase-activated receptor 1 antibody|Thrombin receptor antibody|TR antibody|Anti-Thrombin Receptor antibody (ab32611)
SCBT cat No: To be updated

 

Name

Cleaved-Thrombin R (S42) Polyclonal Antibody

Catalogue No.

STJ90103

Reactivity

Human

Specificity

Cleaved-Thrombin R (S42) Polyclonal Antibody detects endogenous levels of fragment of activated Thrombin R protein resulting from cleavage adjacent to S42.

Immunogen

Synthesized peptide derived from Cleaved-Thrombin R (S42) at AA range 40-120

Host

Rabbit

Applications

WB, ELISA

Recommended dilution

WB 1:500-1:2000; ELISA 1:20000;

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

46 kDa

Formulation

Cleaved-Thrombin R (S42) Antibody was tube-contained. Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

Cleaved-Thrombin R (S42) Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Proteinase-activated receptor 1 antibody, PAR-1 antibody, Coagulation factor II receptor antibody, Thrombin receptor antibody

Database links

Human UniProt/Swiss-Prot:P25116;Mouse UniPort/Swiss-Prot: P30558;Rat UniProt/Swiss-Port: Q5U324;Human Entrez Gene: 2149;Mouse Entrez Gene: 14062;Rat Entrez Gene: Rn.2609

Protein names

Proteinase-activated receptor 1 , PAR-1 , Coagulation factor II receptor , Thrombin receptor

Protein function

High affinity receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation and in vascular development.

Protein tissue specificity

Platelets and vascular endothelial cells.

Protein sequence and domain

The cleaved signal peptide may not be degraded and may function as an intracellular angiogenesis inhibitor peptide known as parstatin. / Belongs to the G-protein coupled receptor 1 family.

Protein post-translational modifications

A proteolytic cleavage generates a new N-terminus that functions as a tethered ligand. / Phosphorylated in the C-terminal tail; probably mediating desensitization prior to the uncoupling and internalization of the receptor.

Protein cellular localization

Cell membrane; Multi-pass membrane protein

Research area

All research areas>Membrane Receptors>PAR
(View all antibody categories related to Membrane Receptors)

Note

AntibodyPlus can customize Cleaved-Thrombin R (S42) Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

Reviews


There are no reviews yet.

Only logged in customers who have purchased this product may leave a review

There are no reviews for this product yet.
By submitting a review, get following benefits:

1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!

view database submit reviews

There is no extra validation for this product yet.
Check other extra validated antibodies below:



Welcome to AntibodyPlus!