Rabbit polyclonal COIL antibody (A6428)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

Clear
-$50 as credit for submitting review for primary antibody
Shipping notice:
Product will be delivered in 6 to 8 Business Days

Rabbit polyclonal COIL antibody (A6428)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:100

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal COIL antibody.

Alternative names:

Check alternative names for the antibody

Expand

CLN80 antibody, p80-coilin antibody
CLN 80 antibody|CLN80 antibody|COIL antibody|COIL_HUMAN antibody|Coilin antibody|Coilin p80 antibody|p80 antibody|P80 coilin antibody|Anti-Coilin antibody [IH10] (ab87913)

SCBT cat No: sc-135871|sc-55595|sc-55594|sc-32860|sc-26109|sc-56298|

Name

Rabbit polyclonal COIL antibody

Catalogue No.

A6428

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human COIL

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:100

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 62kDa/Observed: Refer to Figures

Formulation

COIL antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

COIL antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

CLN80 antibody, p80-coilin antibody

Database links

Human UniProt/Swiss-Prot:P38432

Protein names

CLN80, p80-coilin

Protein function

Component of nuclear coiled bodies, also known as Cajal bodies or CBs, which are involved in the modification and assembly of nucleoplasmic snRNPs.

Protein tissue specificity

Found in all the cell types examined.

Protein sequence and domain

The atypical Tudor domain at the C-terminus contains two large unstructured loops, and does not bind methylated residues.Belongs to the coilin family.; Contains 1 Tudor domain.

Protein post-translational modifications

Symmetrical dimethylation of arginine residues within the RG repeat region enhances affinity for SMN, and thus localization of SMN complexes to CBs.; Phosphorylation during mitosis is associated with disassembly of CBs.

Protein cellular localization

Nucleus . Nucleus, Cajal body .

Background

The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome 4 and chromosome 14.

Note

AntibodyPlus can customize COIL antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

Reviews


There are no reviews yet.

Only logged in customers who have purchased this product may leave a review

There are no reviews for this product yet.
By submitting a review, get following benefits:

1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!

view database submit reviews

There is no extra validation for this product yet.
Check other extra validated antibodies below:



Welcome to AntibodyPlus!