Rabbit polyclonal COL4A5 antibody (A9809)

$69.00$259.00

Reactivity: Human
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal COL4A5 antibody (A9809)

Supplier: ABclonal Inc.

Recommended applications: WB

Recommended dilution:

WB 1:500 – 1:2000

Recommended protocols: check protocols

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Alternative names:

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SCBT cat No:

Name

Rabbit polyclonal COL4A5 antibody

Catalogue No.

A9809

Reactivity

Human

Immunogen

Recombinant protein of human COL4A5

Host

Rabbit

Applications

WB

Recommended dilution

WB 1:500 – 1:2000

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 161kDa/Observed: Refer to figures

Formulation

COL4A5 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

COL4A5 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Database links

Human UniProt/Swiss-Prot:P29400

Protein function

Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a ‘chicken-wire’ meshwork together with laminins, proteoglycans and entactin/nidogen.

Protein tissue specificity

Isoform 2 is found in kidney.

Protein sequence and domain

Alpha chains of type IV collagen have a non-collagenous domain (NC1) at their C-terminus, frequent interruptions of the G-X-Y repeats in the long central triple-helical domain (which may cause flexibility in the triple helix), and a short N-terminal triple-helical 7S domain.Belongs to the type IV collagen family.; Contains 1 collagen IV NC1 (C-terminal non-collagenous) domain.

Protein post-translational modifications

Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains.; Type IV collagens contain numerous cysteine residues which are involved in inter- and intramolecular disulfide bonding. 12 of these, located in the NC1 domain, are conserved in all known type IV collagens.; The trimeric structure of the NC1 domains is stabilized by covalent bonds between Lys and Met residues.

Protein cellular localization

Secreted, extracellular space, extracellular matrix, basement membrane.

Research area

All research areas>Cell Adhesion Proteins>Collagen
(View all antibody categories related to Cell Adhesion Proteins)

Note

AntibodyPlus can customize COL4A5 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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