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Rabbit polyclonal COL4A5 antibody (A9809)
Supplier: ABclonal Inc.
Recommended applications: WB
WB 1:500 – 1:2000
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit polyclonal COL4A5 antibody.
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SCBT cat No:
Rabbit polyclonal COL4A5 antibody
|Catalogue No.|| |
Recombinant protein of human COL4A5
|Recommended dilution|| |
WB 1:500 – 1:2000
|Molecular weight|| |
Predicted: 161kDa/Observed: Refer to figures
COL4A5 antibody was tube-contained.
COL4A5 antibody was purified using affinity purification.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Database links|| |
|Protein function|| |
Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a ‘chicken-wire’ meshwork together with laminins, proteoglycans and entactin/nidogen.
|Protein tissue specificity|| |
Isoform 2 is found in kidney.
|Protein sequence and domain|| |
Alpha chains of type IV collagen have a non-collagenous domain (NC1) at their C-terminus, frequent interruptions of the G-X-Y repeats in the long central triple-helical domain (which may cause flexibility in the triple helix), and a short N-terminal triple-helical 7S domain.Belongs to the type IV collagen family.; Contains 1 collagen IV NC1 (C-terminal non-collagenous) domain.
|Protein post-translational modifications|| |
Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains.; Type IV collagens contain numerous cysteine residues which are involved in inter- and intramolecular disulfide bonding. 12 of these, located in the NC1 domain, are conserved in all known type IV collagens.; The trimeric structure of the NC1 domains is stabilized by covalent bonds between Lys and Met residues.
|Protein cellular localization|| |
Secreted, extracellular space, extracellular matrix, basement membrane.
AntibodyPlus can customize COL4A5 antibody according to your requirement, including bulk product size,etc. Please contact firstname.lastname@example.org. AntibodyPlus provides antibody trial sample for your own antibody validation.
|Product type|| |
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