Rabbit polyclonal COL5A1 antibody (A1515)

$69.00$259.00

Reactivity: Human,Mouse
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal COL5A1 antibody (A1515)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal COL5A1 antibody.

Alternative names:

Check alternative names for the antibody

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COL5A1 antibody, collagen antibody, type V antibody, alpha 1 antibody, collagen alpha-1(V) chain antibody
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SCBT cat No:

Name

Rabbit polyclonal COL5A1 antibody

Catalogue No.

A1515

Reactivity

Human, Mouse

Immunogen

A synthetic peptide of human COL5A1

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 184kDa/Observed: Refer to Figures

Formulation

COL5A1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

COL5A1 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

COL5A1 antibody, collagen antibody, type V antibody, alpha 1 antibody, collagen alpha-1(V) chain antibody

Database links

Human UniProt/Swiss-Prot:P20908

Protein names

COL5A1, collagen, type V, alpha 1, collagen alpha-1(V) chain

Protein function

Type V collagen is a member of group I collagen (fibrillar forming collagen). It is a minor connective tissue component of nearly ubiquitous distribution. Type V collagen binds to DNA, heparan sulfate, thrombospondin, heparin, and insulin.

Protein sequence and domain

The C-terminal propeptide, also known as COLFI domain, have crucial roles in tissue growth and repair by controlling both the intracellular assembly of procollagen molecules and the extracellular assembly of collagen fibrils. It binds a calcium ion which is essential for its function (By similarity).Belongs to the fibrillar collagen family.; Contains 1 fibrillar collagen NC1 domain.; Contains 1 laminin G-like domain.

Protein post-translational modifications

Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains.; Sulfated on 40% of tyrosines.

Protein cellular localization

Secreted, extracellular space, extracellular matrix .

Background

The extensive family of COL gene products (collagens) is composed of several chain types, including fibril-forming interstitial collagens (types I, II, III and V) and basement membrane collagens (type IV), each type containing multiple isoforms. Collagens are fibrous, extracellular matrix proteins with high tensile strength and are the major components of connective tissue, such as tendons and cartilage. All collagens contain a triple helix domain and frequently show lateral self-association in order to form complex connective tissues. Several collagens also play a role in cell adhesion, important for maintaining normal tissue architecture and function.

Research area

All research areas>Cell Adhesion Proteins>Collagen
(View all antibody categories related to Cell Adhesion Proteins)

Note

AntibodyPlus can customize COL5A1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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