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Rabbit polyclonal COPE antibody (A10047)
Supplier: ABclonal Inc.
Recommended applications: WB
WB 1:500 – 1:2000
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit polyclonal COPE antibody.
Check alternative names for the antibodyExpand
1110005D17Rik antibody|Coatomer epsilon subunit antibody|Coatomer protein complex subunit epsilon antibody|Coatomer subunit epsilon antibody|COPE antibody|COPE_HUMAN antibody|Cope1 antibody|Epsilon coat protein antibody|Epsilon COP antibody|Epsilon COP I antibody|Epsilon subunit of coatomer protein complex antibody|Epsilon-coat protein antibody|Epsilon-COP antibody|FLJ13241 antibody|Anti-COPE antibody [EPR12579] (ab180946)
SCBT cat No: sc-133195|sc-133194|sc-166046|sc-12104|sc-25561|
Rabbit polyclonal COPE antibody
|Catalogue No.|| |
Recombinant protein of human COPE
|Recommended dilution|| |
WB 1:500 – 1:2000
|Molecular weight|| |
Predicted: 34kDa/Observed: Refer to figures
COPE antibody was tube-contained.
COPE antibody was purified using affinity purification.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Database links|| |
|Protein function|| |
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated with ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors (By similarity).
|Protein sequence and domain|| |
Belongs to the COPE family.
|Protein post-translational modifications|| |
Phosphorylated by PKA.; Polyubiquitinated by RCHY1 in the presence of androgen, leading to proteasomal degradation.
|Protein cellular localization|| |
Cytoplasm . Golgi apparatus membrane ; Peripheral membrane protein ; Cytoplasmic side . Cytoplasmic vesicle, COPI-coated vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Note: The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it.
AntibodyPlus can customize COPE antibody according to your requirement, including bulk product size,etc. Please contact firstname.lastname@example.org. AntibodyPlus provides antibody trial sample for your own antibody validation.
|Product type|| |
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