Rabbit polyclonal COPE antibody (A10047)

$69.00$259.00

Reactivity: Human,Mouse
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal COPE antibody (A10047)

Supplier: ABclonal Inc.

Recommended applications: WB

Recommended dilution:

WB 1:500 – 1:2000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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1110005D17Rik antibody|Coatomer epsilon subunit antibody|Coatomer protein complex subunit epsilon antibody|Coatomer subunit epsilon antibody|COPE antibody|COPE_HUMAN antibody|Cope1 antibody|Epsilon coat protein antibody|Epsilon COP antibody|Epsilon COP I antibody|Epsilon subunit of coatomer protein complex antibody|Epsilon-coat protein antibody|Epsilon-COP antibody|FLJ13241 antibody|Anti-COPE antibody [EPR12579] (ab180946)

SCBT cat No: sc-133195|sc-133194|sc-166046|sc-12104|sc-25561|

Name

Rabbit polyclonal COPE antibody

Catalogue No.

A10047

Reactivity

Human, Mouse

Immunogen

Recombinant protein of human COPE

Host

Rabbit

Applications

WB

Recommended dilution

WB 1:500 – 1:2000

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 34kDa/Observed: Refer to figures

Formulation

COPE antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

COPE antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Database links

Human UniProt/Swiss-Prot:O14579

Protein function

The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated with ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors (By similarity).

Protein sequence and domain

Belongs to the COPE family.

Protein post-translational modifications

Phosphorylated by PKA.; Polyubiquitinated by RCHY1 in the presence of androgen, leading to proteasomal degradation.

Protein cellular localization

Cytoplasm . Golgi apparatus membrane ; Peripheral membrane protein ; Cytoplasmic side . Cytoplasmic vesicle, COPI-coated vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Note: The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it.

Note

AntibodyPlus can customize COPE antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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