Rabbit polyclonal COPS2 antibody (A7037)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal COPS2 antibody (A7037)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:100

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal COPS2 antibody.

Alternative names:

Check alternative names for the antibody

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CSN2 antibody, SGN2 antibody, ALIEN antibody, TRIP15 antibody
ALIEN antibody|Alien Drosophila himolog of antibody|Alien homolog antibody|COP 9 antibody|COP9 antibody|COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis) antibody|COP9 constitutive photomorphogenic homolog subunit 2 antibody|COP9 signalosome complex subunit 2 antibody|COPS 2 antibody|Cops2 antibody|CSN2 antibody|CSN2_HUMAN antibody|JAB1 containing signalosome subunit 2 antibody|JAB1-containing signalosome subunit 2 antibody|SGN 2 antibody|SGN2 antibody|Signalosome subunit 2 antibody|Thyroid Hormone Receptor Interactor15 antibody|Thyroid Hormone Receptor Interactor 15 antibody|Thyroid receptor-interacting protein 15 antibody|TR-interacting protein 15 antibody|TRIP 15 antibody|TRIP-15 antibody|TRIP15 antibody|Anti-TRIP15 antibody (ab155774)

SCBT cat No:

Name

Rabbit polyclonal COPS2 antibody

Catalogue No.

A7037

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human COPS2

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:100

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 52kDa/Observed: Refer to figures

Formulation

COPS2 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

COPS2 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

CSN2 antibody, SGN2 antibody, ALIEN antibody, TRIP15 antibody

Database links

Human UniProt/Swiss-Prot:P61201

Protein names

CSN2, SGN2, ALIEN, TRIP15

Protein function

Essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively. Involved in early stage of neuronal differentiation via its interaction with NIF3L1.

Protein sequence and domain

Belongs to the CSN2 family.; Contains 1 PCI domain.

Protein post-translational modifications

Phosphorylated by CK2 and PKD kinases.

Protein cellular localization

Cytoplasm . Nucleus .

Research area

All research areas>Signaling Intermediates>TRIP15
(View all antibody categories related to Signaling Intermediates)

Note

AntibodyPlus can customize COPS2 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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