Rabbit polyclonal CP antibody (A7658)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal CP antibody (A7658)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:100

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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CP-2 antibody
CERU_HUMAN antibody|Ceruloplasmin antibody|CP 2 antibody|CP antibody|CP2 antibody|Ferroxidase antibody|Anti-Ceruloplasmin antibody (ab48614)

SCBT cat No: sc-69767|sc-135866|sc-365206|sc-365205|sc-20957|sc-21240|

Name

Rabbit polyclonal CP antibody

Catalogue No.

A7658

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human CP

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:100

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 122kDa/Observed: Refer to figures

Formulation

CP antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

CP antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

CP-2 antibody

Database links

Human UniProt/Swiss-Prot:P00450

Protein names

CP-2

Protein function

Ceruloplasmin is a blue, copper-binding (6-7 atoms per molecule) glycoprotein. It has ferroxidase activity oxidizing Fe(2+) to Fe(3+) without releasing radical oxygen species. It is involved in iron transport across the cell membrane. Provides Cu(2+) ions for the ascorbate-mediated deaminase degradation of the heparan sulfate chains of GPC1. May also play a role in fetal lung development or pulmonary antioxidant defense (By similarity).

Protein tissue specificity

Expressed by the liver and secreted in plasma.

Protein sequence and domain

Belongs to the multicopper oxidase family.; Contains 3 F5/8 type A domains.; Contains 6 plastocyanin-like domains.

Protein cellular localization

Secreted. Note: Colocalizes with GCP1 in secretory intracellular compartments.

Background

The protein encoded by this gene is a metalloprotein that binds most of the copper in plasma and is involved in the peroxidation of Fe(II)transferrin to Fe(III) transferrin. Mutations in this gene cause aceruloplasminemia, which results in iron accumulation and tissue damage, and is associated with diabetes and neurologic abnormalities. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene.

Note

AntibodyPlus can customize CP antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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