Rabbit polyclonal CPLX2 antibody (A7774)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal CPLX2 antibody (A7774)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal CPLX2 antibody.

Alternative names:

Check alternative names for the antibody

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CPX2 antibody, Hfb1 antibody, 921-L antibody, CPX-2 antibody
921 L antibody|Complexin 2 antibody|Complexin II antibody|Complexin-2 antibody|Complexin2 antibody|ComplexinII antibody|CPLX 2 antibody|Cplx2 antibody|CPLX2_HUMAN antibody|CPX 2 antibody|CPX II antibody|CPXII antibody|Hfb1 antibody|Synaphin 1 antibody|Synaphin-1 antibody|Synaphin1 antibody|Anti-CPLX2 antibody (ab215046)

SCBT cat No:

Name

Rabbit polyclonal CPLX2 antibody

Catalogue No.

A7774

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human CPLX2

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 15kDa/Observed: Refer to figures

Formulation

CPLX2 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

CPLX2 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

CPX2 antibody, Hfb1 antibody, 921-L antibody, CPX-2 antibody

Database links

Human UniProt/Swiss-Prot:Q6PUV4

Protein names

CPX2, Hfb1, 921-L, CPX-2

Protein function

Negatively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. Positively regulates a late step in exocytosis of various cytoplasmic vesicles, such as synaptic vesicles and other secretory vesicles. Also involved in mast cell exocytosis (By similarity).

Protein tissue specificity

Nervous system. In hippocampus and cerebellum, expressed mainly by excitatory neurons. Down-regulated in brain cortex from patients suffering from Huntington disease, bipolar disorder or major depression. Down-regulated in cerebellum from patients with schizophrenia.

Protein sequence and domain

Belongs to the complexin/synaphin family.

Protein cellular localization

Cytoplasm, cytosol. Note: Enriched at synaptic-releasing sites in mature neurons.

Background

Proteins encoded by the complexin/synaphin gene family are cytosolic proteins that function in synaptic vesicle exocytosis. These proteins bind syntaxin, part of the SNAP receptor. The protein product of this gene binds to the SNAP receptor complex and disrupts it, allowing transmitter release. Two transcript variants encoding the same protein have been found for this gene.

Note

AntibodyPlus can customize CPLX2 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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