Rabbit polyclonal CRABP2 antibody (A6119)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal CRABP2 antibody (A6119)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:20 – 1:100

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

Expand

RBP6 antibody, CRABP-II antibody
Cellular retinoic acid binding protein 2 antibody|Cellular retinoic acid binding protein II antibody|Cellular retinoic acid-binding protein 2 antibody|Cellular retinoic acid-binding protein II antibody|CRABP II antibody|CRABP-II antibody|Crabp2 antibody|CRABPII antibody|RABP2_HUMAN antibody|RBP6 antibody|Rretinoic acid-binding protein, cellular, type II antibody|Anti-CRABP2 antibody [EPR17376] (ab211927)

SCBT cat No: sc-166897|sc-10065|

Name

Rabbit polyclonal CRABP2 antibody

Catalogue No.

A6119

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human CRABP2

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:20 – 1:100

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 15kDa/Observed: Refer to Figures

Formulation

CRABP2 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

CRABP2 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

RBP6 antibody, CRABP-II antibody

Database links

Human UniProt/Swiss-Prot:P29373

Protein names

RBP6, CRABP-II

Protein function

Transports retinoic acid to the nucleus. Regulates the access of retinoic acid to the nuclear retinoic acid receptors.

Protein sequence and domain

Forms a beta-barrel structure that accommodates hydrophobic ligands in its interior.Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

Protein post-translational modifications

Sumoylated in response to retinoic acid binding, sumoylation is critical for dissociation from ER and subsequent nuclear translocation.

Protein cellular localization

Cytoplasm. Endoplasmic reticulum. Nucleus. Note: Upon ligand binding, a conformation change exposes a nuclear localization motif and the protein is transported into the nucleus.

Background

This gene encodes a member of the retinoic acid (RA, a form of vitamin A) binding protein family and lipocalin/cytosolic fatty-acid binding protein family. The protein is a cytosol-to-nuclear shuttling protein, which facilitates RA binding to its cognate receptor complex and transfer to the nucleus. It is involved in the retinoid signaling pathway, and is associated with increased circulating low-density lipoprotein cholesterol. Alternatively spliced transcript variants encoding the same protein have been found for this gene.

Research area

All research areas>Transport and Trafficking>CRABP
(View all antibody categories related to Transport and Trafficking)

Note

AntibodyPlus can customize CRABP2 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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