Rabbit polyclonal CRADD antibody (A1124)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal CRADD antibody (A1124)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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CRADD antibody,MGC9163 antibody,RAIDD antibody
CASP2 and RIPK1 domain containing adaptor with death domain antibody|Caspase and RIP adapter with death domain antibody|Caspase and RIP adaptor with death domain antibody|Cradd antibody|CRADD_HUMAN antibody|Death adaptor molecule RAIDD antibody|Death domain containing protein CRADD antibody|Death domain-containing protein CRADD antibody|MGC9163 antibody|RIP associated ICH1/CED3 homologous protein with death domain antibody|RIP associated protein with a death domain antibody|RIP-associated protein with a death domain antibody|Anti-RAIDD antibody [EPR1640Y] (ab52621)

SCBT cat No: sc-374447|sc-374448|sc-7880|sc-377080|

Name

Rabbit polyclonal CRADD antibody

Catalogue No.

A1124

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human CRADD

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 23kDa/Observed: Refer to Figures

Formulation

CRADD antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

CRADD antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

CRADD antibody,MGC9163 antibody,RAIDD antibody

Database links

Human UniProt/Swiss-Prot:P78560

Protein names

CRADD,MGC9163,RAIDD

Protein function

Apoptotic adaptor molecule specific for caspase-2 and FASL/TNF receptor-interacting protein RIP. In the presence of RIP and TRADD, CRADD recruits caspase-2 to the TNFR-1 signalling complex.

Protein tissue specificity

Constitutively expressed in most tissues, with particularly high expression in adult heart, testis, liver, skeletal muscle, fetal liver and kidney.

Protein sequence and domain

Contains a death domain involved in the binding of RIP protein.; The CARD domain mediates the interaction with caspase-2.Contains 1 CARD domain.; Contains 1 death domain.

Protein cellular localization

Cytoplasm . Nucleus .

Background

The protein encoded by this gene is a death domain (CARD/DD)-containing protein and has been shown to induce cell apoptosis. Through its CARD domain, this protein interacts with, and thus recruits, caspase 2/ICH1 to the cell death signal transduction complex that includes tumor necrosis factor receptor 1 (TNFR1A), RIPK1/RIP kinase, and numbers of other CARD domain-containing proteins. [provided by RefSeq, Jul 2008]

Note

AntibodyPlus can customize CRADD antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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