Rabbit polyclonal CST3 antibody (A1561)

$69.00$259.00

Reactivity: Human
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal CST3 antibody (A1561)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:100 IF 1:10 – 1:100

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

Expand

ARMD11 antibody, MGC117328 antibody,CST3 antibody
AD 8 antibody|AD8 antibody|Amyloid angiopathy and cerebral hemorrhage antibody|ARMD11 antibody|bA218C14.4 (cystatin C) antibody|bA218C14.4 antibody|Cst 3 antibody|Cst3 antibody|CST3 protein antibody|Cystatin 3 antibody|Cystatin-3 antibody|Cystatin-C antibody|Cystatin3 antibody|CystatinC antibody|CYTC_HUMAN antibody|Gamma trace antibody|Gamma-trace antibody|HCCAA antibody|MGC117328 antibody|Neuroendocrine basic polypeptide antibody|Post gamma globulin antibody|Post-gamma-globulin antibody|Anti-Cystatin C antibody [EPR4413] (ab109508)

SCBT cat No: sc-293159|sc-73878|sc-51857|sc-66100|sc-16989|sc-73879|

Name

Rabbit polyclonal CST3 antibody

Catalogue No.

A1561

Reactivity

Human

Immunogen

Recombinant protein of human CST3

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:100
IF 1:10 – 1:100

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 16kDa/Observed: Refer to Figures

Formulation

CST3 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

CST3 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

ARMD11 antibody, MGC117328 antibody,CST3 antibody

Database links

Human UniProt/Swiss-Prot:P01034

Protein names

ARMD11, MGC117328,CST3

Protein function

As an inhibitor of cysteine proteinases, this protein is thought to serve an important physiological role as a local regulator of this enzyme activity.

Protein tissue specificity

Expressed in submandibular and sublingual saliva but not in parotid saliva (at protein level). Expressed in various body fluids, such as the cerebrospinal fluid and plasma. Expressed in highest levels in the epididymis, vas deferens, brain, thymus, and ovary and the lowest in the submandibular gland.

Protein sequence and domain

Belongs to the cystatin family.

Protein post-translational modifications

The Thr-25 variant is O-glycosylated with a core 1 or possibly core 8 glycan. The signal peptide of the O-glycosylated Thr-25 variant is cleaved between Ala-20 and Val-21.

Protein cellular localization

Secreted .

Background

Cystatin C is a 14 kDa member of the Cystatin superfamily of cysteine protease inhibitors (1). Most cell types secrete Cystatin C (1). Cystatin C inhibits cathepsins, and thereby may function as a tumor suppressor by inhibiting cathepsin mediated tumor cell invasion (2). In addition, this tumor suppressor function can also be attributed to Cystatin C’s ability to antagonize TGF-beta1 signaling (2,3). Cystatin C may also modulate antigen presentation through its ability to inhibit cathepsins (4). Cystatin C is also a biomarker for kidney dysfunction (5).

Research area

All research areas>Signaling Intermediates>Cystatin
(View all antibody categories related to Signaling Intermediates)

Note

AntibodyPlus can customize CST3 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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