Rabbit polyclonal CTH antibody (A6121)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal CTH antibody (A6121)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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CGL_HUMAN antibody|CTH antibody|cystathionase (cystathionine gamma-lyase) antibody|Cystathionine gamma lyase antibody|Cystathionine gamma-lyase antibody|Cysteine desulfhydrase antibody|Gamma cystathionase antibody|Gamma-cystathionase antibody|Homoserine deaminase antibody|Homoserine dehydratase antibody|MGC9471 antibody|Anti-Cystathionase antibody (ab54573)

SCBT cat No: sc-365381|sc-365382|sc-374249|sc-101924|sc-131905|

Name

Rabbit polyclonal CTH antibody

Catalogue No.

A6121

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human CTH

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 44kDa/Observed: Refer to Figures

Formulation

CTH antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

CTH antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Database links

Human UniProt/Swiss-Prot:P32929

Protein function

Catalyzes the last step in the trans-sulfuration pathway from methionine to cysteine. Has broad substrate specificity. Converts cystathionine to cysteine, ammonia and 2-oxobutanoate. Converts two cysteine molecules to lanthionine and hydrogen sulfide. Can also accept homocysteine as substrate. Specificity depends on the levels of the endogenous substrates. Generates the endogenous signaling molecule hydrogen sulfide (H2S), and so contributes to the regulation of blood pressure. Acts as a cysteine-protein sulfhydrase by mediating sulfhydration of target proteins: sulfhydration consists of converting -SH groups into -SSH on specific cysteine residues of target proteins such as GAPDH, PTPN1 and NF-kappa-B subunit RELA, thereby regulating their function.

Protein sequence and domain

Belongs to the trans-sulfuration enzymes family.

Protein cellular localization

Cytoplasm.

Background

This gene encodes a cytoplasmic enzyme in the trans-sulfuration pathway that converts cystathione derived from methionine into cysteine. Glutathione synthesis in the liver is dependent upon the availability of cysteine. Mutations in this gene cause cystathioninuria. Alternative splicing of this gene results in three transcript variants encoding different isoforms.

Note

AntibodyPlus can customize CTH antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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