Rabbit polyclonal CTSD antibody (A1594)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal CTSD antibody (A1594)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:10 – 1:100

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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CPSD antibody, CLN10 antibody
CatD antibody|CATD_HUMAN antibody|Cathepsin D antibody|Cathepsin D heavy chain antibody|CD antibody|Ceroid lipofuscinosis neuronal 10 antibody|CLN10 antibody|CPSD antibody|ctsd antibody|Epididymis secretory sperm binding protein Li 130P antibody|HEL S 130P antibody|Lysosomal aspartyl peptidase antibody|Lysosomal aspartyl protease antibody|MGC2311 antibody|Anti-Cathepsin D antibody [CTD-19] (ab6313)

SCBT cat No: sc-136282|sc-53927|sc-6486|sc-377124|sc-377299|sc-13148|sc-374381|sc-6494|sc-10725|sc-6488|sc-6487|

Name

Rabbit polyclonal CTSD antibody

Catalogue No.

A1594

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant Protein of human CTSD

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:10 – 1:100

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 45kDa/Observed: Refer to Figures

Formulation

CTSD antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

CTSD antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

CPSD antibody, CLN10 antibody

Database links

Human UniProt/Swiss-Prot:P07339

Protein names

CPSD, CLN10

Protein function

Acid protease active in intracellular protein breakdown. Involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease.

Protein tissue specificity

Expressed in the aorta extrcellular space (at protein level).

Protein sequence and domain

Belongs to the peptidase A1 family.; Contains 1 peptidase A1 domain.

Protein post-translational modifications

N- and O-glycosylated.

Protein cellular localization

Lysosome. Melanosome. Secreted, extracellular space. Note: Identified by mass spectrometry in melanosome fractions from stage I to stage IV. In aortic samples, detected as an extracellular protein loosely bound to the matrix .

Background

This gene encodes a lysosomal aspartyl protease composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. This proteinase, which is a member of the peptidase C1 family, has a specificity similar to but narrower than that of pepsin A. Transcription of this gene is initiated from several sites, including one which is a start site for an estrogen-regulated transcript. Mutations in this gene are involved in the pathogenesis of several diseases, including breast cancer and possibly Alzheimer disease.

Note

AntibodyPlus can customize CTSD antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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