Rabbit polyclonal CTSE antibody (A2678)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal CTSE antibody (A2678)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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CATE antibody
CATE antibody|CATE_HUMAN antibody|Cathepsin E antibody|Cathepsin E form II antibody|CTSE antibody|Erythrocyte membrane aspartic proteinase antibody|Slow moving proteinase antibody|Anti-Cathepsin E antibody (ab36996)

SCBT cat No: sc-166286|sc-6508|sc-166501|sc-166500|sc-166285|sc-166343|sc-30055|

Name

Rabbit polyclonal CTSE antibody

Catalogue No.

A2678

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human CTSE

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 43kDa/Observed: Refer to Figures

Formulation

CTSE antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

CTSE antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

CATE antibody

Database links

Human UniProt/Swiss-Prot:P14091

Protein names

CATE

Protein function

May have a role in immune function. Probably involved in the processing of antigenic peptides during MHC class II-mediated antigen presentation. May play a role in activation-induced lymphocyte depletion in the thymus, and in neuronal degeneration and glial cell activation in the brain.

Protein tissue specificity

Expressed abundantly in the stomach, the Clara cells of the lung and activated B-lymphocytes, and at lower levels in lymph nodes, skin and spleen. Not expressed in resting B-lymphocytes.

Protein sequence and domain

Belongs to the peptidase A1 family.; Contains 1 peptidase A1 domain.

Protein post-translational modifications

Glycosylated. The nature of the carbohydrate chain varies between cell types. In fibroblasts, the proenzyme contains a high mannose-type oligosaccharide, while the mature enzyme contains a complex-type oligosaccharide. In erythrocyte membranes, both the proenzyme and mature enzyme contain a complex-type oligosaccharide.; Two forms are produced by autocatalytic cleavage, form I begins at Ile-54, form II begins at Thr-57.

Protein cellular localization

Endosome . Note: The proenzyme is localized to the endoplasmic reticulum and Golgi apparatus, while the mature enzyme is localized to the endosome.

Background

The protein encoded by this gene is a gastric aspartyl protease that functions as a disulfide-linked homodimer. This protease, which is a member of the peptidase C1 family, has a specificity similar to that of pepsin A and cathepsin D. It is an intracellular proteinase that does not appear to be involved in the digestion of dietary protein and is found in highest concentration in the surface of epithelial mucus-producing cells of the stomach. It is the first aspartic proteinase expressed in the fetal stomach and is found in more than half of gastric cancers. It appears, therefore, to be an oncofetal antigen. Transcript variants utilizing alternative polyadenylation signals and two transcript variants encoding different isoforms exist for this gene. [provided by RefSeq, Jul 2008]

Research area

All research areas>Synthesis and Degradation>Cathepsin
(View all antibody categories related to Synthesis and Degradation)

Note

AntibodyPlus can customize CTSE antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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