Rabbit polyclonal CUL5 antibody (A5369)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal CUL5 antibody (A5369)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal CUL5 antibody.

Alternative names:

Check alternative names for the antibody

Expand

VACM1 antibody, VACM-1 antibody
CUL 5 antibody|CUL-5 antibody|CUL5 antibody|CUL5_HUMAN antibody|Cullin-5 (vasopressin-activated calcium-mobilizing receptor-1) antibody|Cullin-5 antibody|Cullin5 antibody|VACM 1 antibody|VACM-1 antibody|VACM1 antibody|Vasopressin activated calcium mobilizing receptor 1 antibody|Vasopressin activated calcium mobilizing receptor antibody|Vasopressin-activated calcium-mobilizing receptor 1 antibody|Vasopressin-activated calcium-mobilizing receptor-1 antibody|Anti-Cullin 5 antibody [EPR14725] (ab184177)

SCBT cat No: sc-373822|

Name

Rabbit polyclonal CUL5 antibody

Catalogue No.

A5369

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human CUL5

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 91kDa/Observed: Refer to Figures

Formulation

CUL5 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

CUL5 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

VACM1 antibody, VACM-1 antibody

Database links

Human UniProt/Swiss-Prot:Q93034

Protein names

VACM1, VACM-1

Protein function

Core component of multiple SCF-like ECS (Elongin-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimulated by adenovirus E1B-55 kDa protein. May form a cell surface vasopressin receptor.

Protein sequence and domain

Belongs to the cullin family.

Protein post-translational modifications

Neddylated; which enhances the ubiquitination activity of SCF and prevents binding of the inhibitor CAND1. Deneddylated via its interaction with the COP9 signalosome (CSN).

Research area

All research areas>Cell Cycle Proteins>CUL
(View all antibody categories related to Cell Cycle Proteins)

Note

AntibodyPlus can customize CUL5 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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