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Rabbit polyclonal CYBB antibody (A1636)
$69.00–$259.00
Reactivity: Human,Mouse,Rat
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.
Rabbit polyclonal CYBB antibody (A1636)
Supplier: ABclonal Inc.
Recommended applications: WB
Recommended dilution:
WB 1:500 – 1:2000
Recommended protocols: check protocols
Image descriptions:
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Alternative names:
Check alternative names for the antibody
ExpandCGD antibody, GP91-1 antibody, GP91-PHOX antibody, GP91PHOX antibody, NOX2 antibody, p91-PHOX antibody
AMCBX2 antibody|CGD antibody|CGD91-phox antibody|CY24B_HUMAN antibody|CYBB antibody|Cytochrome b 245, beta polypeptide antibody|Cytochrome b(558) beta chain antibody|Cytochrome b(558) subunit beta antibody|Cytochrome b-245 heavy chain antibody|Cytochrome b558 subunit beta antibody|GP91 PHOX antibody|gp91-1 antibody|gp91-phox antibody|GP91PHOX antibody|Heme-binding membrane glycoprotein gp91phox antibody|NADPH oxidase 2 antibody|Neutrophil cytochrome b 91 kDa polypeptide antibody|NOX2 antibody|p22 phagocyte B-cytochrome antibody|P91 PHOX antibody|p91-PHOX antibody|Superoxide-generating NADPH oxidase heavy chain subunit antibody|Anti-NOX2/gp91phox antibody (ab80508)
SCBT cat No: sc-130543|sc-5827|sc-130549|sc-27635|sc-74514|sc-20782|sc-5826|sc-130548|
| Name | Rabbit polyclonal CYBB antibody |
|---|---|
| Catalogue No. | A1636 |
| Reactivity | Human, Mouse, Rat |
| Immunogen | Recombinant protein of human CYBB |
| Host | Rabbit |
| Applications | WB |
| Recommended dilution | WB 1:500 – 1:2000 |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Molecular weight | Predicted: 65kDa/Observed: Refer to Figures |
| Formulation | CYBB antibody was tube-contained. |
| Purification | CYBB antibody was purified using affinity purification. |
| Storage | Store at -20 Celsius degree. Avoid freeze / thaw cycles. |
| Alternative antibody names | CGD antibody, GP91-1 antibody, GP91-PHOX antibody, GP91PHOX antibody, NOX2 antibody, p91-PHOX antibody |
| Database links | Human UniProt/Swiss-Prot:P04839 |
| Protein names | CGD, GP91-1, GP91-PHOX, GP91PHOX, NOX2, p91-PHOX |
| Protein function | Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membrane to molecular oxygen on the exterior. Also functions as a voltage-gated proton channel that mediates the H(+) currents of resting phagocytes. It participates in the regulation of cellular pH and is blocked by zinc. |
| Protein tissue specificity | Detected in neutrophils (at protein level). |
| Protein sequence and domain | Contains 1 FAD-binding FR-type domain.; Contains 1 ferric oxidoreductase domain. |
| Protein post-translational modifications | Glycosylated.; Phosphorylated on Ser and Thr residues. |
| Protein cellular localization | Cell membrane; Multi-pass membrane protein. |
| Background | Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell’s respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole. [provided by RefSeq, Jul 2008] |
| Research area | All research areas>Synthesis and Degradation>gp91-phox |
| Note | AntibodyPlus can customize CYBB antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation. |
| Product type | Primary antibody |
| Supplier | ABclonal Inc. |
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