Rabbit polyclonal CYCS antibody (A0225)


Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

-$50 as credit for submitting review for primary antibody
Shipping notice:
Product will be delivered in 6 to 8 Business Days

Rabbit polyclonal CYCS antibody (A0225)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:1000 IHC 1:50 – 1:200 IF 1:10 – 1:100

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal CYCS antibody.

Alternative names:

Check alternative names for the antibody


CYCS antibody,CYC antibody,HCS antibody,THC4 antibody
CYC antibody|CYC_HUMAN antibody|CYCS antibody|Cytochrome c antibody|Cytochrome c somatic antibody|HCS antibody|THC4 antibody|Anti-Cytochrome C antibody [7H8.2C12] (ab13575)

SCBT cat No: sc-65396|sc-13561|sc-13560|sc-13156|sc-8385|sc-7159|


Rabbit polyclonal CYCS antibody

Catalogue No.



Human, Mouse, Rat


Recombinant protein of human CYCS





Recommended dilution

WB 1:500 – 1:1000
IHC 1:50 – 1:200
IF 1:10 – 1:100







Molecular weight

Predicted: 12kDa/Observed: Refer to Figures


CYCS antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.


CYCS antibody was purified using affinity purification.


Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

CYCS antibody,CYC antibody,HCS antibody,THC4 antibody

Database links

Human UniProt/Swiss-Prot:P99999

Protein names


Protein function

Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.; Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.

Protein sequence and domain

Belongs to the cytochrome c family.

Protein post-translational modifications

Binds 1 heme group per subunit.; Phosphorylation at Tyr-49 and Tyr-98 both reduce by half the turnover in the reaction with cytochrome c oxidase, down-regulating mitochondrial respiration.

Protein cellular localization

Mitochondrion intermembrane space. Note: Loosely associated with the inner membrane.


Cytochrome c is a well conserved electron-transport protein and is part of the respiratory chain localized to mitochondrial intermembrane space (1). Upon apoptotic stimulation, cytochrome c released from mitochondria associates with procaspase-9 (47 kDa)/Apaf 1. This complex processes caspase-9 from inactive proenzyme to its active form (2). This event further triggers caspase-3 activation and eventually leads to apoptosis (3).

Research area

All research areas>Tumor Suppressor/Apoptosis>Cytochrome
(View all antibody categories related to Tumor Suppressor/Apoptosis)


AntibodyPlus can customize CYCS antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody


ABclonal Inc.


There are no reviews yet.

Only logged in customers who have purchased this product may leave a review

There are no reviews for this product yet.
By submitting a review, get following benefits:

1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!

view database submit reviews

There is no extra validation for this product yet.
Check other extra validated antibodies below:

Welcome to AntibodyPlus!