Rabbit polyclonal CYP2F1 antibody (A7550)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal CYP2F1 antibody (A7550)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal CYP2F1 antibody.

Alternative names:

Check alternative names for the antibody

Expand

C2F1 antibody, CYP2F antibody
CP2F1_HUMAN antibody|CYP2F1 antibody|CYPIIF1 antibody|Cytochrome P450 2F1 antibody|cytochrome P450, family 2, subfamily F, polypeptide 1 antibody|Anti-CYP2F1 antibody – C-terminal (ab135815)

SCBT cat No: sc-377499|sc-67282|sc-374470|sc-374540|sc-67283|

Name

Rabbit polyclonal CYP2F1 antibody

Catalogue No.

A7550

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human CYP2F1

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 56kDa/Observed: Refer to figures

Formulation

CYP2F1 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

CYP2F1 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

C2F1 antibody, CYP2F antibody

Database links

Human UniProt/Swiss-Prot:P24903

Protein names

C2F1, CYP2F

Protein function

May be involved in the metabolism of various pneumotoxicants including naphthalene. Is able to dealkylate ethoxycoumarin, propoxycoumarin, and pentoxyresorufin but possesses no activity toward ethoxyresorufin and only trace dearylation activity toward benzyloxyresorufin. Bioactivates 3-methylindole (3MI) by dehydrogenation to the putative electrophile 3-methylene-indolenine.

Protein tissue specificity

Expressed in lung. Rarely detected in liver and placenta.

Protein sequence and domain

Belongs to the cytochrome P450 family.

Protein cellular localization

Endoplasmic reticulum membrane ; Peripheral membrane protein . Microsome membrane ; Peripheral membrane protein .

Background

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to dehydrogenate 3-methylindole, an endogenous toxin derived from the fermentation of tryptophan, as well as xenobiotic substrates such as naphthalene and ethoxycoumarin. This gene is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q.

Research area

All research areas>Synthesis and Degradation>CYP
(View all antibody categories related to Synthesis and Degradation)

Note

AntibodyPlus can customize CYP2F1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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