Rabbit polyclonal CYP3A5 antibody (A7663)

$69.00$259.00

Reactivity: Human
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal CYP3A5 antibody (A7663)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for Rabbit polyclonal CYP3A5 antibody.

Alternative names:

Check alternative names for the antibody

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CP35 antibody, PCN3 antibody, CYPIIIA5 antibody, P450PCN3 antibody
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SCBT cat No:

Name

Rabbit polyclonal CYP3A5 antibody

Catalogue No.

A7663

Reactivity

Human

Immunogen

Recombinant protein of human CYP3A5

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 57kDa/Observed: Refer to figures

Formulation

CYP3A5 antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

CYP3A5 antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

CP35 antibody, PCN3 antibody, CYPIIIA5 antibody, P450PCN3 antibody

Database links

Human UniProt/Swiss-Prot:P20815

Protein names

CP35, PCN3, CYPIIIA5, P450PCN3

Protein function

Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.

Protein sequence and domain

Belongs to the cytochrome P450 family.

Protein cellular localization

Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.

Background

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein metabolizes drugs as well as the steroid hormones testosterone and progesterone. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Two pseudogenes of this gene have been identified within this cluster on chromosome 7. Expression of this gene is widely variable among populations, and a single nucleotide polymorphism that affects transcript splicing has been associated with susceptibility to hypertensions. Alternative splicing results in multiple transcript variants.

Research area

All research areas>Synthesis and Degradation>CYP
(View all antibody categories related to Synthesis and Degradation)

Note

AntibodyPlus can customize CYP3A5 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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