Rabbit polyclonal DAO antibody (A5309)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal DAO antibody (A5309)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

Expand

DAAO antibody, OXDA antibody, DAMOX antibody
D-amino-acid oxidase antibody|DAAO antibody|DAMOX antibody|DAO antibody|DAO1 antibody|EC 1.4.3.3 antibody|MGC35381 antibody|OXDA antibody|OXDA_HUMAN antibody|Anti-D Amino Acid Oxidase antibody [EPR7555] (ab140127)

SCBT cat No: sc-398757|sc-26077|sc-292768|sc-26078|

Name

Rabbit polyclonal DAO antibody

Catalogue No.

A5309

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human DAO

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 39kDa/Observed: Refer to Figures

Formulation

DAO antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

DAO antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

DAAO antibody, OXDA antibody, DAMOX antibody

Database links

Human UniProt/Swiss-Prot:P14920

Protein names

DAAO, OXDA, DAMOX

Protein function

Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids.

Protein sequence and domain

Belongs to the DAMOX/DASOX family.

Protein cellular localization

Peroxisome.

Background

This gene encodes the peroxisomal enzyme D-amino acid oxidase. The enzyme is a flavoprotein which uses flavin adenine dinucleotide (FAD) as its prosthetic group. Its substrates include a wide variety of D-amino acids, but it is inactive on the naturally occurring L-amino acids. Its biological function is not known; it may act as a detoxifying agent which removes D-amino acids that accumulate during aging. In mice, it degrades D-serine, a co-agonist of the NMDA receptor. This gene may play a role in the pathophysiology of schizophrenia.

Note

AntibodyPlus can customize DAO antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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