Rabbit polyclonal DARS antibody (A6574)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB,IHC
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal DARS antibody (A6574)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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HBSL antibody, aspRS antibody
Aspartate tRNA ligase 1 cytoplasmic antibody|Aspartate tRNA ligase antibody|Aspartate–tRNA ligase antibody|Aspartyl tRNA synthetase antibody|Aspartyl tRNA synthetase cytoplasmic antibody|Aspartyl-tRNA synthetase antibody|AspRS antibody|Cell proliferation inducing gene 40 protein antibody|Cell proliferation inducing protein 40 antibody|Cell proliferation-inducing gene 40 protein antibody|cytoplasmic antibody|Dars antibody|DKFZp781B11202 antibody|MGC111579 antibody|SYDC_HUMAN antibody|Anti-DARS antibody (ab151974)

SCBT cat No: sc-100986|sc-366018|sc-393275|

Name

Rabbit polyclonal DARS antibody

Catalogue No.

A6574

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human DARS

Host

Rabbit

Applications

WB, IHC

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 57kDa/Observed: Refer to figures

Formulation

DARS antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

DARS antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

HBSL antibody, aspRS antibody

Database links

Human UniProt/Swiss-Prot:P14868

Protein names

HBSL, aspRS

Protein function

Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA.

Protein tissue specificity

Expression in the developing and adult brain shows similar patterns. Highly expressed in the ventricular and subventricular zones, including hippocampal subfields, the midlateral temporaal cortex and the frontal polar cortex. The cerebellum, cereral cortex, hippocampus, and lateral ventricle show preferential neuronal expression. Expression in the peripheral neurons is evident in the colon.

Protein sequence and domain

Belongs to the class-II aminoacyl-tRNA synthetase family.

Protein cellular localization

Cytoplasm.

Background

This gene encodes a member of a multienzyme complex that functions in mediating the attachment of amino acids to their cognate tRNAs. The encoded protein ligates L-aspartate to tRNA(Asp). Mutations in this gene have been found in patients showing hypomyelination with brainstem and spinal cord involvement and leg spasticity. Alternative splicing results in multiple transcript variants.

Note

AntibodyPlus can customize DARS antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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