Rabbit polyclonal DCD antibody (A7280)

$69.00$259.00

Reactivity: Human,Mouse
Applications: WB,IHC,IF
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal DCD antibody (A7280)

Supplier: ABclonal Inc.

Recommended applications: WB,IHC,IF

Recommended dilution:

WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:50 – 1:100

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

Expand

PIF antibody, AIDD antibody, DSEP antibody, HCAP antibody, DCD-1 antibody
AIDD antibody|DCD 1 antibody|dcd antibody|DCD-1 antibody|DCD_HUMAN antibody|DSEP antibody|HCAP antibody|PIF antibody|Preproteolysin antibody|Anti-Dermcidin antibody – C-terminal (ab175519)

SCBT cat No: sc-27467|sc-393728|sc-33656|sc-398429|sc-32926|sc-27465|

Name

Rabbit polyclonal DCD antibody

Catalogue No.

A7280

Reactivity

Human, Mouse

Immunogen

Recombinant protein of human DCD

Host

Rabbit

Applications

WB, IHC, IF

Recommended dilution

WB 1:500 – 1:2000
IHC 1:50 – 1:200
IF 1:50 – 1:100

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 11kDa/Observed: Refer to figures

Formulation

DCD antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

DCD antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

PIF antibody, AIDD antibody, DSEP antibody, HCAP antibody, DCD-1 antibody

Database links

Human UniProt/Swiss-Prot:P81605

Protein names

PIF, AIDD, DSEP, HCAP, DCD-1

Protein function

DCD-1 displays antimicrobial activity thereby limiting skin infection by potential pathogens in the first few hours after bacterial colonization. Highly effective against E.coli, E.faecalis, S.aureus and C.albicans. Optimal pH and salt concentration resemble the conditions in sweat. Also exhibits proteolytic activity.; Survival-promoting peptide promotes survival of neurons and displays phosphatase activity. It may bind IgG.

Protein tissue specificity

Specifically and constitutively expressed in eccrine sweat gland cells. Secreted into the sweat at a concentration of 1-10 micrograms/ml.

Protein cellular localization

Secreted.

Background

This antimicrobial gene encodes a secreted protein that is subsequently processed into mature peptides of distinct biological activities. The C-terminal peptide is constitutively expressed in sweat and has antibacterial and antifungal activities. The N-terminal peptide, also known as diffusible survival evasion peptide, promotes neural cell survival under conditions of severe oxidative stress. A glycosylated form of the N-terminal peptide may be associated with cachexia (muscle wasting) in cancer patients. Alternative splicing results in multiple transcript variants encoding different isoforms.

Note

AntibodyPlus can customize DCD antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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