Rabbit polyclonal DCXR antibody (A4721)

$69.00$259.00

Reactivity: Human,Mouse,Rat
Applications: WB
Conjugation: Unconjugated
Supplier: ABclonal Inc.

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Rabbit polyclonal DCXR antibody (A4721)

Supplier: ABclonal Inc.

Recommended applications: WB

Recommended dilution:

WB 1:500 – 1:2000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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XR antibody, DCR antibody, HCR2 antibody, P34H antibody, HCRII antibody, KIDCR antibody, PNTSU antibody, SDR20C1 antibody
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SCBT cat No: sc-100552|sc-292501|

Name

Rabbit polyclonal DCXR antibody

Catalogue No.

A4721

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein of human DCXR

Host

Rabbit

Applications

WB

Recommended dilution

WB 1:500 – 1:2000

Clonality

Polyclonal

Conjugation

Unconjugated

Isotype

IgG

Molecular weight

Predicted: 26kDa/Observed: Refer to figures

Formulation

DCXR antibody was tube-contained.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification

DCXR antibody was purified using affinity purification.

Storage

Store at -20 Celsius degree. Avoid freeze / thaw cycles.

Alternative antibody names

XR antibody, DCR antibody, HCR2 antibody, P34H antibody, HCRII antibody, KIDCR antibody, PNTSU antibody, SDR20C1 antibody

Database links

Human UniProt/Swiss-Prot:Q7Z4W1

Protein names

XR, DCR, HCR2, P34H, HCRII, KIDCR, PNTSU, SDR20C1

Protein function

Catalyzes the NADPH-dependent reduction of several pentoses, tetroses, trioses, alpha-dicarbonyl compounds and L-xylulose. Participates in the uronate cycle of glucose metabolism. May play a role in the water absorption and cellular osmoregulation in the proximal renal tubules by producing xylitol, an osmolyte, thereby preventing osmolytic stress from occurring in the renal tubules.

Protein tissue specificity

Highly expressed in kidney, liver and epididymis. In the epididymis, it is mainly expressed in the proximal and distal sections of the corpus region. Weakly or not expressed in brain, lung, heart, spleen and testis.

Protein sequence and domain

Belongs to the short-chain dehydrogenases/reductases (SDR) family.

Protein cellular localization

Membrane ; Peripheral membrane protein . Note: Probably recruited to membranes via an interaction with phosphatidylinositol.

Background

The protein encoded by this gene acts as a homotetramer to catalyze diacetyl reductase and L-xylulose reductase reactions. The encoded protein may play a role in the uronate cycle of glucose metabolism and in the cellular osmoregulation in the proximal renal tubules. Defects in this gene are a cause of pentosuria. Two transcript variants encoding different isoforms have been found for this gene.

Note

AntibodyPlus can customize DCXR antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provides antibody trial sample for your own antibody validation.

Product type

Primary antibody

Supplier

ABclonal Inc.

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