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Rabbit polyclonal DDX20 antibody (A5817)
Supplier: ABclonal Inc.
Recommended applications: WB,IHC,IF
WB 1:500 – 1:2000 IHC 1:50 – 1:200 IF 1:10 – 1:100
Recommended protocols: check protocols
Click or hover above images to see image description for Rabbit polyclonal DDX20 antibody.
Check alternative names for the antibodyExpand
DP103 antibody, GEMIN3 antibody
Component of gems 3 antibody|DDX 20 antibody|ddx20 antibody|DDX20_HUMAN antibody|DEAD (Asp Glu Ala Asp) box polypeptide 20 antibody|DEAD box protein 20 antibody|DEAD box protein DP 103 antibody|DEAD box protein DP103 antibody|DEAD/H (Asp Glu Ala Asp/His) box polypeptide 20 103kD antibody|DEAD/H (Asp Glu Ala Asp/His) box polypeptide 20 antibody|DEAD/H BOX 20 antibody|DKFZP434H052 antibody|DP 103 antibody|DP103 antibody|Gemin-3 antibody|Gemin3 antibody|Probable ATP dependent RNA helicase DDX20 antibody|Probable ATP-dependent RNA helicase ddx20 antibody|SMN interacting protein antibody|Anti-Gemin 3 antibody [12H12] (ab10305)
SCBT cat No: sc-57007|sc-135919|sc-374373|sc-271853|sc-50405|
Rabbit polyclonal DDX20 antibody
|Catalogue No.|| |
Human, Mouse, Rat
Recombinant protein of human DDX20
WB, IHC, IF
|Recommended dilution|| |
WB 1:500 – 1:2000
|Molecular weight|| |
Predicted: 92kDa/Observed: Refer to Figures
DDX20 antibody was tube-contained.
DDX20 antibody was purified using affinity purification.
Store at -20 Celsius degree. Avoid freeze / thaw cycles.
|Alternative antibody names|| |
DP103 antibody, GEMIN3 antibody
|Database links|| |
|Protein names|| |
|Protein function|| |
The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus. May also play a role in the metabolism of small nucleolar ribonucleoprotein (snoRNPs).
|Protein tissue specificity|| |
|Protein sequence and domain|| |
Belongs to the DEAD box helicase family. DDX20 subfamily.; Contains 1 helicase ATP-binding domain.; Contains 1 helicase C-terminal domain.
|Protein cellular localization|| |
Cytoplasm. Nucleus, gem. Note: Localized in subnuclear structures next to coiled bodies, called Gemini of Cajal bodies (Gems).
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which has an ATPase activity and is a component of the survival of motor neurons (SMN) complex. This protein interacts directly with SMN, the spinal muscular atrophy gene product, and may play a catalytic role in the function of the SMN complex on RNPs.
AntibodyPlus can customize DDX20 antibody according to your requirement, including bulk product size,etc. Please contact email@example.com. AntibodyPlus provides antibody trial sample for your own antibody validation.
|Product type|| |
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